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Database: UniProt
Entry: G8JPM1_ERECY
LinkDB: G8JPM1_ERECY
Original site: G8JPM1_ERECY 
ID   G8JPM1_ERECY            Unreviewed;       120 AA.
AC   G8JPM1;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   10-APR-2019, entry version 29.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 9 {ECO:0000256|RuleBase:RU364145};
DE   AltName: Full=Mediator complex subunit 9 {ECO:0000256|RuleBase:RU364145};
GN   Name=MED9 {ECO:0000256|RuleBase:RU364145};
GN   OrderedLocusNames=Ecym_2117 {ECO:0000313|EMBL:AET37870.1};
OS   Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166
OS   / NRRL Y-17582) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=931890 {ECO:0000313|EMBL:AET37870.1, ECO:0000313|Proteomes:UP000006790};
RN   [1] {ECO:0000313|Proteomes:UP000006790}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582
RC   {ECO:0000313|Proteomes:UP000006790};
RX   DOI=10.1534/g3.111.000745;
RA   Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA   Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA   Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA   Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M.,
RA   Mallet S., Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J.,
RA   Seret M.L., Talla E., Samson G., Jubin C., Poulain J., Vacherie B.,
RA   Barbe V., Pelletier E., Sherman D.J., Westhof E., Weissenbach J.,
RA   Baret P.V., Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT   "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps
RT   of genome resolution following polyploidization.";
RL   G3 (Bethesda) 2:299-311(2012).
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator
CC       involved in the regulated transcription of nearly all RNA
CC       polymerase II-dependent genes. Mediator functions as a bridge to
CC       convey information from gene-specific regulatory proteins to the
CC       basal RNA polymerase II transcription machinery. Mediator is
CC       recruited to promoters by direct interactions with regulatory
CC       proteins and serves as a scaffold for the assembly of a functional
CC       preinitiation complex with RNA polymerase II and the general
CC       transcription factors. {ECO:0000256|RuleBase:RU364145}.
CC   -!- SUBUNIT: Component of the Mediator complex.
CC       {ECO:0000256|RuleBase:RU364145}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU364145}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 9 family.
CC       {ECO:0000256|RuleBase:RU364145}.
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DR   EMBL; CP002498; AET37870.1; -; Genomic_DNA.
DR   RefSeq; XP_003644687.1; XM_003644639.1.
DR   STRING; 45285.XP_003644687.1; -.
DR   EnsemblFungi; AET37870; AET37870; Ecym_2117.
DR   GeneID; 11470509; -.
DR   KEGG; erc:Ecym_2117; -.
DR   eggNOG; ENOG410J48B; Eukaryota.
DR   eggNOG; ENOG41115PD; LUCA.
DR   InParanoid; G8JPM1; -.
DR   KO; K15150; -.
DR   OrthoDB; 1598182at2759; -.
DR   Proteomes; UP000006790; Chromosome 2.
DR   GO; GO:0070847; C:core mediator complex; IEA:EnsemblFungi.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:EnsemblFungi.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:EnsemblFungi.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:EnsemblFungi.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:EnsemblFungi.
DR   GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IEA:EnsemblFungi.
DR   InterPro; IPR011425; Med9.
DR   Pfam; PF07544; Med9; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|RuleBase:RU364145};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006790};
KW   Nucleus {ECO:0000256|RuleBase:RU364145};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006790};
KW   Transcription {ECO:0000256|RuleBase:RU364145};
KW   Transcription regulation {ECO:0000256|RuleBase:RU364145}.
SQ   SEQUENCE   120 AA;  14012 MW;  BC9F845772603566 CRC64;
     MSEPPASDRT LNNQTLNQVY ATLTKNTSQQ PEFIPQIFYA LHQFKEDSKS GGNSLETATS
     SIRHRIKLCK SYLREDPHCI ELLSRPYEDW PQVVEQKQQE IETKKLVHKQ LGERIRAMIR
//
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