ID   G8JQJ0_ERECY            Unreviewed;       608 AA.
AC   G8JQJ0;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   RecName: Full=Translation initiation factor eIF2B subunit delta {ECO:0000256|ARBA:ARBA00044147};
DE   AltName: Full=eIF2B GDP-GTP exchange factor subunit delta {ECO:0000256|ARBA:ARBA00044356};
GN   OrderedLocusNames=Ecym_2610 {ECO:0000313|EMBL:AET38323.1};
OS   Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 /
OS   NRRL Y-17582) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=931890 {ECO:0000313|EMBL:AET38323.1, ECO:0000313|Proteomes:UP000006790};
RN   [1] {ECO:0000313|Proteomes:UP000006790}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582
RC   {ECO:0000313|Proteomes:UP000006790};
RX   DOI=10.1534/g3.111.000745;
RA   Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA   Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA   Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA   Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA   Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA   Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA   Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA   Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT   "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT   genome resolution following polyploidization.";
RL   G3 (Bethesda) 2:299-311(2012).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
CC   -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC       {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
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DR   EMBL; CP002498; AET38323.1; -; Genomic_DNA.
DR   RefSeq; XP_003645140.1; XM_003645092.1.
DR   AlphaFoldDB; G8JQJ0; -.
DR   STRING; 931890.G8JQJ0; -.
DR   GeneID; 11471939; -.
DR   KEGG; erc:Ecym_2610; -.
DR   eggNOG; KOG1467; Eukaryota.
DR   HOGENOM; CLU_016218_3_4_1; -.
DR   InParanoid; G8JQJ0; -.
DR   OMA; IPRCIAM; -.
DR   OrthoDB; 169924at2759; -.
DR   Proteomes; UP000006790; Chromosome 2.
DR   GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR   InterPro; IPR000649; IF-2B-related.
DR   InterPro; IPR042529; IF_2B-like_C.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   PANTHER; PTHR10233; TRANSLATION INITIATION FACTOR EIF-2B; 1.
DR   PANTHER; PTHR10233:SF14; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA; 1.
DR   Pfam; PF01008; IF-2B; 1.
DR   SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006790}.
FT   REGION          1..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          526..557
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..61
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        77..91
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..113
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   608 AA;  67720 MW;  E59A48710625A96A CRC64;
     MSAELANIPP ISKQKVPKEV PKQTSENGNP ASKDPDGSDE KKLSNKELKD LKKKEKAAKR
     AAQKQASGIT VEQQKQQAQL KKEKKQQQRE QQLSGNKKGK NNKPPTSDIS RKSTLFGHLE
     TTEERRASLL AVTSAISSVR SSKITATGLM IPTVSHMLSS SIPTVPPSVT HSTSSAGSQT
     ADSTVQVLTN VSVDDDSSFV PGTSSVISLA MEENFKNSQL VSSVKELVAN KDLLHPTVAL
     LTSEFASYKI VGSIPRCLAM MEAFQIVIRD YKTPEGTTLS RNLTSYLSHQ IDFLKKARPL
     SVTMGNAIRW LKQEISLIDP TTSDLKAKDT LCEKIAQFAC EKVELADQLI LESASQHIDH
     NSTILTYGCS KVLTDLFIYN SVELKKNFQI VIVDSRPLFE GRRMAEILRR KGLNITYVLI
     TSLATIFNMD INYVFLGAHS ILSNGFLYSR VGTAMLAMSA KRRNIPVLVF CESLKFSQRV
     QLDSVTFNEL ADPNALVEIS SDNPVKRRSN KGFLLQRFVK ERKDYMKQKD EQDTKQNNSN
     KTKIETEERK DEPDKPILAD WQNLPNLDIF NIMYDLTPPE YIQKVITEFG ALPPSSVPVI
     LREYKGSA
//