ID G8JUH3_ERECY Unreviewed; 1589 AA.
AC G8JUH3;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=THO complex subunit 2 {ECO:0000256|ARBA:ARBA00019596};
GN OrderedLocusNames=Ecym_6378 {ECO:0000313|EMBL:AET40753.1};
OS Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 /
OS NRRL Y-17582) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=931890 {ECO:0000313|EMBL:AET40753.1, ECO:0000313|Proteomes:UP000006790};
RN [1] {ECO:0000313|Proteomes:UP000006790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582
RC {ECO:0000313|Proteomes:UP000006790};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the THOC2 family.
CC {ECO:0000256|ARBA:ARBA00007857}.
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DR EMBL; CP002502; AET40753.1; -; Genomic_DNA.
DR RefSeq; XP_003647570.1; XM_003647522.1.
DR STRING; 931890.G8JUH3; -.
DR GeneID; 11469140; -.
DR KEGG; erc:Ecym_6378; -.
DR eggNOG; KOG1874; Eukaryota.
DR HOGENOM; CLU_003123_0_0_1; -.
DR InParanoid; G8JUH3; -.
DR OMA; GIEFMKY; -.
DR OrthoDB; 179356at2759; -.
DR Proteomes; UP000006790; Chromosome 6.
DR GO; GO:0000347; C:THO complex; IEA:InterPro.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR InterPro; IPR040007; Tho2.
DR InterPro; IPR021418; THO_THOC2_C.
DR InterPro; IPR021726; THO_THOC2_N.
DR InterPro; IPR032302; THOC2_N.
DR PANTHER; PTHR21597:SF0; THO COMPLEX SUBUNIT 2; 1.
DR PANTHER; PTHR21597; THO2 PROTEIN; 1.
DR Pfam; PF11262; Tho2; 1.
DR Pfam; PF11732; Thoc2; 1.
DR Pfam; PF16134; THOC2_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000006790}.
FT DOMAIN 22..635
FT /note="THO complex subunit 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16134"
FT DOMAIN 642..715
FT /note="THO complex subunitTHOC2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11732"
FT DOMAIN 923..1177
FT /note="THO complex subunitTHOC2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11262"
FT REGION 345..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1390..1589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1204..1231
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 360..382
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1420..1461
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1479..1505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1524..1570
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1589 AA; 183492 MW; 06FA962277232562 CRC64;
MSIIGKLNSL AKEHTPFKRT IFTDEFLKDW QGNSSKLLER YDSIEESSEK DNLIYDIFNE
AMVFTNKEFK DLLNDDYGML GEFLSKLCEK NSQANPRMLA NIINYFPRSL EDDSNVIALI
GAIRGVDFEF SASLVEKLLT HRWTKEQTSL YKRNLISEKY HLKKYNLLFE CAPGFSQICS
LLHVAYSDKD RFQSLKYYWN QMQFIAGKYT LDPIRVLDVV LRISSIYIHN HYDFLLDLLK
VSDYWPHEIS DPFDWNKLNY GGNVVASRLI AYKLSNEKFD HKYMDMVCIL IKEGFISYIS
IFEALRPDEE TVQTYVEEYY ADLEKQSSEG VLNPLAMAAA LPDEDETSAP AANGEQKSDG
QVNVKKEKER QEQREEKERK NRHYRVKRTG KWRLVTSCLN HGLLFPALYS IKKNEKVALS
IDALVEACIR IFDYMIQPLY EQAINAPKCN AVSRVTMKMS NSGLPSKEPR LIHEYVSPNV
SERFLFNVKY SFYYTEWTDK LPVLHNIEDL FRYSHQILGL LGPRLSVSSS VITKLNSIAV
HDIESSNNSE DTIEMWINYF RKFIFPAIAA IEDDFVPNLS AYELMKRFPF EKRYFLYNEM
YTKTSNDNVF VRLAFNKVGK RIKTLLKSLS IDDIADKVND VSRIVSSNPL AALGPIVNQI
ENYDKVSELV VISANKFPKI AYDILQYVLL LKLTSGRNLL QSDGINQNTW IQRLSVFIAG
LAKSCPEMDL TNILTFLVKS LHKNRNVSFP VLKELISKVG GIQNLNHVSS QQLQMLNSGP
SLQKVARSLI LDTRQDTFEA ARAITQVFVK LNAITELIVM LCNLNISNQS DDIHYKILST
KCDDSNSLLW TLIEMLKHTL SLEEFVSNVL PFYELVNDYN VPIEWSFHIW RDFFDEKIHE
GDESMKQIDE IIEKTEFKYV SFENLNKELF TNFWKLSLYD VQFNKALYDK TTSALNSKLN
AVKLQRERNS IMNDVQEVMS NCLAHQRAFK QIQELLQGNK EKWLPELNAE TNQAFFQFCI
LPRTLFSSAD AIYSALFIVE LCGIQNSFSI FKFFVDSHIL GGLLFSCTVT ESANMGFFTN
VLLNTFEKAR SEGVFDNCSL EEIYRLHSIM IGDLTGLLAE SNYMSIRNSI EFLNQISHKF
PVVDEHIKEL CHSLEYKLVG DNREDIRLPC NALIGHLKSR LKNASRKQDF YELPEEELLE
IRKLDEERML IKKYQESLAQ EDEAKKLEEE SKMNILKPLD DRVESRYMAN TGEADSTDAE
KTKQQSEAVS CQLHQILDNM DQVLNLLRTE SAEEAPRFIR VVFFKNEFKK VINDYKGDLE
GFRKNIANIL VDYFYSMVQW PQSNPTFVQK ARDIKTACLK CNAPISKATK IKVMADDLYG
EDIASSWATN PKAARTNRES RFAGAKPVPN LTSDTSTSNE NKWKTERVEK TAIDTRNTSR
YADEDTKSST QTKKDDKPSG SRFNNGKVPV KKPVDNKQDQ KPSNSLRNRV GSRFEGRQEN
STRFSGPRAD PIRFPTAPAR HAEPVNESRF RNMPKELSRK RAAEDYRYGD SKRQRQEDDN
RRKPTKETRG EQHPTAILSQ KKGGFSRFR
//
