ID G8NQ28_GRAMM Unreviewed; 673 AA.
AC G8NQ28;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
DE Flags: Precursor;
GN OrderedLocusNames=AciX8_4081 {ECO:0000313|EMBL:AEU38362.1};
OS Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8).
OC Bacteria; Acidobacteriota; Terriglobia; Terriglobales; Acidobacteriaceae;
OC Granulicella.
OX NCBI_TaxID=682795 {ECO:0000313|EMBL:AEU38362.1, ECO:0000313|Proteomes:UP000007113};
RN [1] {ECO:0000313|EMBL:AEU38362.1, ECO:0000313|Proteomes:UP000007113}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1857 / DSM 23137 / MP5ACTX8
RC {ECO:0000313|Proteomes:UP000007113};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Rawat S., Mannisto M.,
RA Haggblom M., Woyke T.;
RT "Complete sequence of Granulicella mallensis MP5ACTX8.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
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DR EMBL; CP003130; AEU38362.1; -; Genomic_DNA.
DR RefSeq; WP_014267233.1; NC_016631.1.
DR AlphaFoldDB; G8NQ28; -.
DR STRING; 682795.AciX8_4081; -.
DR KEGG; gma:AciX8_4081; -.
DR eggNOG; COG3525; Bacteria.
DR HOGENOM; CLU_007082_5_1_0; -.
DR OrthoDB; 1098018at2; -.
DR Proteomes; UP000007113; Chromosome.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AEU38362.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007113};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..673
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003512175"
FT DOMAIN 29..161
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 165..466
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 321
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 673 AA; 74977 MW; 35FDCFA8A3BB9F16 CRC64;
MLRSIALLAF LCHVVACSSS AAQAPFVNAL VPQPRELQVS ADPGLSFSQT TSVFLQAAAS
GPLSAATSRF IVRLQSTTGI ELTTPLVPNH DAASIVIHVA DASASQPTLG MDESYSLNVD
SHRATIEANT IFGAYHGMET LLQLLQSNGS GWFLPPVHIV DTPRFPWRGL LLDPSRHFLP
VPVLLRTLDA MAAVKMNVLH LHLTDFQGFR IESRVFPRLT ADGSDGEFYT QDQMRAVVAY
AAARGIRIVP EFDMPGHSMS WMAGYPQLAS APGPFHAEHS YHIFAAAMDP TRESTYEFLD
RFFEEMTHIF PDQYVHIGGD ETNGVAWKSN PRIAAYMKAH GYAKPSELQA EFSRRVQRIL
NRHGRKMIGW DEALSPDLLS GFVVQNRRGA TSFAAAATQN RQTIYSQPYY LDHHSSSAEI
YAAKLPTGQG MLGGEACMWG EEVNAQTIDS RVWPRTIAFA ERMWSPPQVS DVEDMYRRLR
IESLRLDAMG LEHLSNPQRL LRHISRSLSS PELETLAATL QPEDFIVRLQ RQKPTRDTPL
VGLVDAVVFD PPFEHEFDRT VDAFLHSTDD AAINQAASTL RRDFQSWVNT GPALDQLTES
NPELKKVTER RHELIALGHL GLEELEARQH HEHLSAPDVA MAEQLLQRAA TPDEGYVDFI
VLQPLEQLLR AVR
//
