ID G8NW12_GRAMM Unreviewed; 474 AA.
AC G8NW12;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Pyrimidine-nucleoside phosphorylase {ECO:0000313|EMBL:AEU35432.1};
DE EC=2.4.2.4 {ECO:0000313|EMBL:AEU35432.1};
GN OrderedLocusNames=AciX8_1086 {ECO:0000313|EMBL:AEU35432.1};
OS Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8).
OC Bacteria; Acidobacteriota; Terriglobia; Terriglobales; Acidobacteriaceae;
OC Granulicella.
OX NCBI_TaxID=682795 {ECO:0000313|EMBL:AEU35432.1, ECO:0000313|Proteomes:UP000007113};
RN [1] {ECO:0000313|EMBL:AEU35432.1, ECO:0000313|Proteomes:UP000007113}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1857 / DSM 23137 / MP5ACTX8
RC {ECO:0000313|Proteomes:UP000007113};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Rawat S., Mannisto M.,
RA Haggblom M., Woyke T.;
RT "Complete sequence of Granulicella mallensis MP5ACTX8.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the thymidine/pyrimidine-nucleoside
CC phosphorylase family. {ECO:0000256|ARBA:ARBA00006915}.
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DR EMBL; CP003130; AEU35432.1; -; Genomic_DNA.
DR RefSeq; WP_014264312.1; NC_016631.1.
DR AlphaFoldDB; G8NW12; -.
DR STRING; 682795.AciX8_1086; -.
DR KEGG; gma:AciX8_1086; -.
DR eggNOG; COG0213; Bacteria.
DR HOGENOM; CLU_025040_0_1_0; -.
DR OrthoDB; 9763887at2; -.
DR Proteomes; UP000007113; Chromosome.
DR GO; GO:0004645; F:1,4-alpha-oligoglucan phosphorylase activity; IEA:InterPro.
DR GO; GO:0016154; F:pyrimidine-nucleoside phosphorylase activity; IEA:InterPro.
DR GO; GO:0009032; F:thymidine phosphorylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006206; P:pyrimidine nucleobase metabolic process; IEA:InterPro.
DR GO; GO:0006213; P:pyrimidine nucleoside metabolic process; IEA:InterPro.
DR Gene3D; 3.40.1030.10; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR Gene3D; 3.90.1170.30; Pyrimidine nucleoside phosphorylase-like, C-terminal domain; 1.
DR InterPro; IPR000312; Glycosyl_Trfase_fam3.
DR InterPro; IPR017459; Glycosyl_Trfase_fam3_N_dom.
DR InterPro; IPR036320; Glycosyl_Trfase_fam3_N_dom_sf.
DR InterPro; IPR035902; Nuc_phospho_transferase.
DR InterPro; IPR036566; PYNP-like_C_sf.
DR InterPro; IPR013102; PYNP_C.
DR InterPro; IPR018090; Pyrmidine_PPas_bac/euk.
DR InterPro; IPR000053; Thymidine/pyrmidine_PPase.
DR NCBIfam; TIGR02644; Y_phosphoryl; 1.
DR PANTHER; PTHR10515; THYMIDINE PHOSPHORYLASE; 1.
DR PANTHER; PTHR10515:SF0; THYMIDINE PHOSPHORYLASE; 1.
DR Pfam; PF02885; Glycos_trans_3N; 1.
DR Pfam; PF00591; Glycos_transf_3; 1.
DR Pfam; PF07831; PYNP_C; 1.
DR PIRSF; PIRSF000478; TP_PyNP; 2.
DR SMART; SM00941; PYNP_C; 1.
DR SUPFAM; SSF52418; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR SUPFAM; SSF47648; Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain; 1.
DR SUPFAM; SSF54680; Pyrimidine nucleoside phosphorylase C-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:AEU35432.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007113};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AEU35432.1}.
FT DOMAIN 379..453
FT /note="Pyrimidine nucleoside phosphorylase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00941"
SQ SEQUENCE 474 AA; 51161 MW; A5B55639ADFC5FA1 CRC64;
MSDHAIYPLD IVIKKRDGAE LTKAEIEHFI HAVVLNGEQK LAEARGEKPA TLSATDKVTD
AQIAAFLMAV FQRGLSPEEL ANLTTAMRFS GETFDAAPLH TFTVDKHSTG GVGDKSSLLI
APIVAAAGLD LSPSISVPMI SGRSLGHTGG TLDKLETIPG FDTQISMARF AEILRECHAS
LVGQTPRLVP ADRILYAMRD HTGTVESPFL ITASIMSKKL AESLNALVLD VKVGSGAFMP
TYEKSKFLAE LMVSTGERAG TRTAALLTTM DEPLGRFSGN WMEVWECVDI LQNRRHPMSA
DLIELSNILS GWMLYFGGKT ATPEAGAKLA DDILRSGAAY KSWLQIVAAH QGDTSIFNDP
AAFHQPKATR VLKASRAGYL AGMDCKEVGW AVQRLGAGRA KPGDPVSAHA GIESHAKLGD
KVEEGQPIFT LFSEDAALLD EPYRMLEATV EIANEPRQKQ PLIREIITKE NIKG
//
