ID G8NYW8_GRAMM Unreviewed; 238 AA.
AC G8NYW8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=DNA-3-methyladenine glycosylase II {ECO:0000256|ARBA:ARBA00012000};
DE EC=3.2.2.21 {ECO:0000256|ARBA:ARBA00012000};
GN OrderedLocusNames=AciX8_0173 {ECO:0000313|EMBL:AEU34531.1};
OS Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8).
OC Bacteria; Acidobacteriota; Terriglobia; Terriglobales; Acidobacteriaceae;
OC Granulicella.
OX NCBI_TaxID=682795 {ECO:0000313|EMBL:AEU34531.1, ECO:0000313|Proteomes:UP000007113};
RN [1] {ECO:0000313|EMBL:AEU34531.1, ECO:0000313|Proteomes:UP000007113}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1857 / DSM 23137 / MP5ACTX8
RC {ECO:0000313|Proteomes:UP000007113};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Lu M., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Rawat S., Mannisto M.,
RA Haggblom M., Woyke T.;
RT "Complete sequence of Granulicella mallensis MP5ACTX8.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-
CC methylguanine, 7-methylguanine and 7-methyladenine.; EC=3.2.2.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000086};
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DR EMBL; CP003130; AEU34531.1; -; Genomic_DNA.
DR RefSeq; WP_014263415.1; NC_016631.1.
DR AlphaFoldDB; G8NYW8; -.
DR STRING; 682795.AciX8_0173; -.
DR KEGG; gma:AciX8_0173; -.
DR eggNOG; COG0122; Bacteria.
DR HOGENOM; CLU_000445_72_5_0; -.
DR OrthoDB; 9785929at2; -.
DR Proteomes; UP000007113; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR CDD; cd00056; ENDO3c; 1.
DR Gene3D; 1.10.1670.40; -; 1.
DR InterPro; IPR011257; DNA_glycosylase.
DR InterPro; IPR003265; HhH-GPD_domain.
DR PANTHER; PTHR43003; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR PANTHER; PTHR43003:SF15; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR Pfam; PF00730; HhH-GPD; 1.
DR SMART; SM00478; ENDO3c; 1.
DR SUPFAM; SSF48150; DNA-glycosylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007113}.
FT DOMAIN 59..228
FT /note="HhH-GPD"
FT /evidence="ECO:0000259|SMART:SM00478"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 238 AA; 26128 MW; D3E15D1D9E0BE3D1 CRC64;
MPRPRSGSTR KLPYDPTEAT DALSAADPKL AKLIAKAGPF TVRLPAQQSP FEALTQSIIY
QQLHGKAAAT IHARLLASFA DACGIGNHPE PQDLLDCPNE QLRAAGLSHN KALALRDLAA
KTLDGTVPTI ARIRRMSDDD IIEHLTQVRG IGKWTVEMML IFRLGRPNVL PSSDYGIRKG
FALTYLGLKP TEKVTPDLLA THEQIAKRAK KWAPWCSVAS WYMWRACDLA AGKTVQPE
//
