ID G8QWN7_SPHPG Unreviewed; 353 AA.
AC G8QWN7;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=3-dehydroquinate synthetase {ECO:0000313|EMBL:AEV28331.1};
GN OrderedLocusNames=SpiGrapes_0476 {ECO:0000313|EMBL:AEV28331.1};
OS Sphaerochaeta pleomorpha (strain ATCC BAA-1885 / DSM 22778 / Grapes).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Sphaerochaetaceae;
OC Sphaerochaeta.
OX NCBI_TaxID=158190 {ECO:0000313|EMBL:AEV28331.1, ECO:0000313|Proteomes:UP000005632};
RN [1] {ECO:0000313|EMBL:AEV28331.1, ECO:0000313|Proteomes:UP000005632}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1885 / DSM 22778 / Grapes
RC {ECO:0000313|Proteomes:UP000005632};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Munk A.C., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Ritalahtilisa K.,
RA Loeffler F., Woyke T.;
RT "Complete sequence of Spirochaeta sp. grapes.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Co(2+); Xref=ChEBI:CHEBI:48828;
CC Evidence={ECO:0000256|ARBA:ARBA00001941};
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
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DR EMBL; CP003155; AEV28331.1; -; Genomic_DNA.
DR RefSeq; WP_014269180.1; NC_016633.1.
DR AlphaFoldDB; G8QWN7; -.
DR STRING; 158190.SpiGrapes_0476; -.
DR KEGG; sgp:SpiGrapes_0476; -.
DR eggNOG; COG0337; Bacteria.
DR HOGENOM; CLU_001201_0_1_12; -.
DR OrthoDB; 9806583at2; -.
DR Proteomes; UP000005632; Chromosome.
DR GO; GO:0016838; F:carbon-oxygen lyase activity, acting on phosphates; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd08195; DHQS; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR030963; DHQ_synth_fam.
DR InterPro; IPR030960; DHQS/DOIS.
DR PANTHER; PTHR43622; 3-DEHYDROQUINATE SYNTHASE; 1.
DR PANTHER; PTHR43622:SF7; 3-DEHYDROQUINATE SYNTHASE, CHLOROPLASTIC; 1.
DR Pfam; PF01761; DHQ_synthase; 1.
DR PIRSF; PIRSF001455; DHQ_synth; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE 4: Predicted;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000005632}.
FT DOMAIN 57..317
FT /note="3-dehydroquinate synthase"
FT /evidence="ECO:0000259|Pfam:PF01761"
SQ SEQUENCE 353 AA; 38838 MW; A76F03109B2B976C CRC64;
MKSLSTTTLA NGKQTEILIA DNLKDLSAHL GSYGRSVLWV FDANTATLFK QLPPVNVVLE
SGESSKNFSS LERILSNAVD EGLARDCRII GFGGGVVCDM AAFAASVFMR GCKLTLVPTT
LLCMVDASVG GKTAIDFKGL KNMVGSFYPA EEVLISMDTL RTLPEKEYLN GLAEVIKHAL
LSQDEQLYKF LLVKKNEILS RDIETLQTLV TLSLAVKQWY IEQDPTETKG IRQVLNLGHT
FGHALESSGH FTFGHGACVA WGTCRALEAG VNMGITDKAY AIGATKLFKS YGYDIDYRIG
RGDWIEFRER LSKDKKKEKG QVLFVLMESQ GKAVLRPIDM ALVQHLVIAK PIF
//
