ID G8QYB6_SPHPG Unreviewed; 569 AA.
AC G8QYB6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=AMP-forming long-chain acyl-CoA synthetase {ECO:0000313|EMBL:AEV30763.1};
GN OrderedLocusNames=SpiGrapes_3013 {ECO:0000313|EMBL:AEV30763.1};
OS Sphaerochaeta pleomorpha (strain ATCC BAA-1885 / DSM 22778 / Grapes).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Sphaerochaetaceae;
OC Sphaerochaeta.
OX NCBI_TaxID=158190 {ECO:0000313|EMBL:AEV30763.1, ECO:0000313|Proteomes:UP000005632};
RN [1] {ECO:0000313|EMBL:AEV30763.1, ECO:0000313|Proteomes:UP000005632}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1885 / DSM 22778 / Grapes
RC {ECO:0000313|Proteomes:UP000005632};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Munk A.C., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Ritalahtilisa K.,
RA Loeffler F., Woyke T.;
RT "Complete sequence of Spirochaeta sp. grapes.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-
CC CoA + AMP + diphosphate; Xref=Rhea:RHEA:15421, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:57287, ChEBI:CHEBI:57560,
CC ChEBI:CHEBI:83139, ChEBI:CHEBI:456215; EC=6.2.1.3;
CC Evidence={ECO:0000256|ARBA:ARBA00024484};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:15422;
CC Evidence={ECO:0000256|ARBA:ARBA00024484};
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DR EMBL; CP003155; AEV30763.1; -; Genomic_DNA.
DR RefSeq; WP_014271602.1; NC_016633.1.
DR AlphaFoldDB; G8QYB6; -.
DR STRING; 158190.SpiGrapes_3013; -.
DR KEGG; sgp:SpiGrapes_3013; -.
DR eggNOG; COG1022; Bacteria.
DR HOGENOM; CLU_000022_59_9_12; -.
DR OrthoDB; 311554at2; -.
DR Proteomes; UP000005632; Chromosome.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43272:SF83; ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J; 1.
DR PANTHER; PTHR43272; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005632}.
FT DOMAIN 32..423
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 569 AA; 63858 MW; 860638CE3BB55FE3 CRC64;
MKHSWEEIDE YRGILFPGKW PTILEMFMIS LQQFPGNKCF TVFTPDRNTM TYTEVYDECS
RIGSYLQQQG LKKGDKVVIN GKNSPQWALA YLSVFYAGGI VVPLDNQMHP DRVGTLSAFC
EASFFFGDSS VIDALSLDAP WVNNLKGVAT LLGRSKHCPT LEELKPTKLY PSVPSSCEDD
AAILFTSGTT GNEKGAVLSH ANIISDVYQA CDGIFLELDD RDVLYALLPL HHSYCCTSVL
LESIRHGSEC VFGHEIAVSK MIVDLTRGNV TIFMGIPLLY NKVLSGMMKQ VKKKGVFVNS
LVHTMMFING IMKKYLHLNP FRKTFNKLLL NKIGLDHNRI CICGAGPLSP KVFKQYQQLG
LDFIQGYGLT ETSPILTLNP ISHFKIESVG MCFPLVDMKI GNPDEKGIGE ILVKGPNVTR
GYYKDKAHTK ELFTEDGYLK TGDLGCLDKE NYLYLKGRAK NLIVTEGGKN VYPEEIEDLF
QLYTQVEQVL IRGYQEKKDV PAECIEAVIY PNMDFFKESK EDPQKNLEAV IKEVNQNLSG
YKKITKLTLI DKPMAMTSTQ KIKRGKVIA
//
