ID G8QYR9_SPHPG Unreviewed; 590 AA.
AC G8QYR9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Xaa-Pro aminopeptidase {ECO:0000313|EMBL:AEV29696.1};
GN OrderedLocusNames=SpiGrapes_1902 {ECO:0000313|EMBL:AEV29696.1};
OS Sphaerochaeta pleomorpha (strain ATCC BAA-1885 / DSM 22778 / Grapes).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Sphaerochaetaceae;
OC Sphaerochaeta.
OX NCBI_TaxID=158190 {ECO:0000313|EMBL:AEV29696.1, ECO:0000313|Proteomes:UP000005632};
RN [1] {ECO:0000313|EMBL:AEV29696.1, ECO:0000313|Proteomes:UP000005632}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1885 / DSM 22778 / Grapes
RC {ECO:0000313|Proteomes:UP000005632};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Munk A.C., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Ritalahtilisa K.,
RA Loeffler F., Woyke T.;
RT "Complete sequence of Spirochaeta sp. grapes.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
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DR EMBL; CP003155; AEV29696.1; -; Genomic_DNA.
DR RefSeq; WP_014270539.1; NC_016633.1.
DR AlphaFoldDB; G8QYR9; -.
DR STRING; 158190.SpiGrapes_1902; -.
DR KEGG; sgp:SpiGrapes_1902; -.
DR eggNOG; COG0006; Bacteria.
DR HOGENOM; CLU_011781_2_4_12; -.
DR OrthoDB; 9806388at2; -.
DR Proteomes; UP000005632; Chromosome.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:AEV29696.1};
KW Hydrolase {ECO:0000313|EMBL:AEV29696.1};
KW Protease {ECO:0000313|EMBL:AEV29696.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005632}.
FT DOMAIN 7..145
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 309..522
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 530..590
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 590 AA; 66072 MW; 3E6BBDF91D869D84 CRC64;
MQTIDKRVQA LRLIMEREGL DAWIVNGTDP HQSEYVCPRW RSREWISGFS GSAGTVVITK
DQALLWVDSR YFIQGAKQIE NSCFTLMKLD TPNVLDPVSY LAQTMDEKSK VGIDGATLMV
SAKEKMEMAF LERGVELISC PDYLDEIWLD RPAVPNTALL ELEAGVAGFT RLQKTTMVRL
AMVQKNCTYT LISSLDDIAW VTNLRGNDIS YSPVFLSYLL LGTDKAWLFT DPSRFSPDLL
ASVGEDLTIV PYEKASETIA SVIKESDTVY CNPEKTNMLV STALGKAKIV TGRDFTTDLK
ACKNETELEG MRRAHLLDGV AMVNFFARLD TENPQYDEIA VSDLLLQQRL RNKGCIGESF
GPISGFGEHG AMCHYSATKE SSAKIEKNGL LVLDTGGMYE FGMTDITRTI LFGEATEEQR
HDYTLVLKGN LALASVRFPQ GTCGYQLDIL ARQFLWQNGM TYFHGTGHGV GFRLNVHEGP
QVINTKPIDI PLKPGMILSD EPGLYKEGKH GIRIENLVVV QEDVKTEFGQ FYGFEVLTLC
PLERKLIDKA MLSKMEISMV DQYHQWVFEE LKDLVDAEAQ AYLRASTLPL
//
