ID G8R2F2_OWEHD Unreviewed; 334 AA.
AC G8R2F2;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family {ECO:0000313|EMBL:AEV32942.1};
GN OrderedLocusNames=Oweho_1963 {ECO:0000313|EMBL:AEV32942.1};
OS Owenweeksia hongkongensis (strain DSM 17368 / CIP 108786 / JCM 12287 / NRRL
OS B-23963 / UST20020801).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Owenweeksiaceae;
OC Owenweeksia.
OX NCBI_TaxID=926562 {ECO:0000313|EMBL:AEV32942.1, ECO:0000313|Proteomes:UP000005631};
RN [1] {ECO:0000313|EMBL:AEV32942.1, ECO:0000313|Proteomes:UP000005631}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 17368 / JCM 12287 / NRRL B-23963
RC {ECO:0000313|Proteomes:UP000005631};
RX PubMed=23450211; DOI=10.4056/sigs.3296896;
RA Riedel T., Held B., Nolan M., Lucas S., Lapidus A., Tice H., Del Rio T.G.,
RA Cheng J.F., Han C., Tapia R., Goodwin L.A., Pitluck S., Liolios K.,
RA Mavromatis K., Pagani I., Ivanova N., Mikhailova N., Pati A., Chen A.,
RA Palaniappan K., Rohde M., Tindall B.J., Detter J.C., Goker M., Woyke T.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P.,
RA Kyrpides N.C.;
RT "Genome sequence of the orange-pigmented seawater bacterium Owenweeksia
RT hongkongensis type strain (UST20020801(T)).";
RL Stand. Genomic Sci. 7:120-130(2012).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP003156; AEV32942.1; -; Genomic_DNA.
DR RefSeq; WP_014202296.1; NC_016599.1.
DR AlphaFoldDB; G8R2F2; -.
DR STRING; 926562.Oweho_1963; -.
DR KEGG; oho:Oweho_1963; -.
DR PATRIC; fig|926562.3.peg.1970; -.
DR eggNOG; COG1013; Bacteria.
DR HOGENOM; CLU_048564_1_0_10; -.
DR OrthoDB; 9775140at2; -.
DR Proteomes; UP000005631; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR CDD; cd03375; TPP_OGFOR; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR011896; OFOB.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR NCBIfam; TIGR02177; PorB_KorB; 1.
DR PANTHER; PTHR48084:SF4; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB; 1.
DR PANTHER; PTHR48084; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB-RELATED; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Pyruvate {ECO:0000313|EMBL:AEV32942.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005631}.
FT DOMAIN 53..200
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 334 AA; 37470 MW; C1511F4C278B194C CRC64;
MSTNATLTAK DFATDQDVRW CPGCGDYSIL KQMQTVLPEL RIERENLVFI SGIGCSSRFP
YYMNSYGMHS IHGRAPAVAA GLKAANPDLS VWVITGDGDG LSIGGNHLIH ALRRNFDINI
LLFNNEIYGL TKGQYSPTSE LGKYTKSSPL GSIDHPFNPL ALALGADATF VARSMDRDPI
HLREILKQAE QHKGTSFVEI YQNCNVFNDG AFEQYTDKKQ KPDTTINLVE GEPLFFSNNT
KAMRLNGWKP EIVEYLDGDS TDDLWIHDSK DPMKAHLLSR MFSDDGPRPF GIFYQEDRFI
YEDAMQNQIN KAIEIQGEGD LDTLIKGKNS WVVE
//
