ID G8R5M5_OWEHD Unreviewed; 951 AA.
AC G8R5M5;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN OrderedLocusNames=Oweho_3391 {ECO:0000313|EMBL:AEV34341.1};
OS Owenweeksia hongkongensis (strain DSM 17368 / CIP 108786 / JCM 12287 / NRRL
OS B-23963 / UST20020801).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Owenweeksiaceae;
OC Owenweeksia.
OX NCBI_TaxID=926562 {ECO:0000313|EMBL:AEV34341.1, ECO:0000313|Proteomes:UP000005631};
RN [1] {ECO:0000313|EMBL:AEV34341.1, ECO:0000313|Proteomes:UP000005631}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 17368 / JCM 12287 / NRRL B-23963
RC {ECO:0000313|Proteomes:UP000005631};
RX PubMed=23450211; DOI=10.4056/sigs.3296896;
RA Riedel T., Held B., Nolan M., Lucas S., Lapidus A., Tice H., Del Rio T.G.,
RA Cheng J.F., Han C., Tapia R., Goodwin L.A., Pitluck S., Liolios K.,
RA Mavromatis K., Pagani I., Ivanova N., Mikhailova N., Pati A., Chen A.,
RA Palaniappan K., Rohde M., Tindall B.J., Detter J.C., Goker M., Woyke T.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P.,
RA Kyrpides N.C.;
RT "Genome sequence of the orange-pigmented seawater bacterium Owenweeksia
RT hongkongensis type strain (UST20020801(T)).";
RL Stand. Genomic Sci. 7:120-130(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; CP003156; AEV34341.1; -; Genomic_DNA.
DR AlphaFoldDB; G8R5M5; -.
DR STRING; 926562.Oweho_3391; -.
DR KEGG; oho:Oweho_3391; -.
DR PATRIC; fig|926562.3.peg.3412; -.
DR eggNOG; COG0178; Bacteria.
DR HOGENOM; CLU_001370_0_2_10; -.
DR Proteomes; UP000005631; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd03271; ABC_UvrA_II; 1.
DR Gene3D; 3.30.190.20; -; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 3.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000005631};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 606..943
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 951 AA; 106175 MW; E69C7E983A17A98D CRC64;
MTQNHPVSEK DQIEVYGARV HNLKNIDVVI PRNELVVITG LSGSGKSSLA FDTIYAEGQR
RYIETFSAYA RQFLGSLERP DVDKINGLSP VISIEQKTTS KNPRSTVGTV TEIYDFLRLL
YARGSVAYSY NTGEKMVSYT DDKIRELIIE QFAGKRINIL APLVRSRKGH YRELFDSILK
QGFVKARIDG EIVDVTKGMR LDRYKTHDIE VVVDRLKVEN DSNDKRLRES ITVAMQQGHG
IIMVVEHGQE KPRFFSRNLM CPSTGISYPE PEPNTFSFNS PKGACPKCNG LGEVSEIDMD
KVIPDPTKSI RKGGLTPLGD YKKTWIFNQL EIIGDKYGFD ITTPIKDIPK KGMDVILHGS
DEAFEVENKN LGITRKYSIN FEGIINFILN QNEEAKSKSI KRWAEGFMNK VPCDQCHGER
LKIESRHFKI GDKNISDLAG MSLGSLQNWL ENIEPELSEN QKQIATEILK ELRTRVSFLL
NVGLNYLSLN RPAKSLSGGE AQRIRLATQI GSQLVNVLYI LDEPSIGLHQ RDNHKLIESL
MELRDVGNSV IVVEHDRDMI EQADYILDIG PHAGRRGGNV VAAGTLQDIL NSHSLTAQYM
NGEKEIAIPE TRREGNGEFI TLKGAKGNNL KNVSVKVPLG KLVVVTGVSG SGKSTLINET
LYPTLSAHFY NSVKKPLEHK SITGLDKIDK VIDIDQSPIG RTPRSNPATY TGVLSYIRDL
FANLPESKVR AYKPGRFSFN VKGGRCETCE GAGIRVIEMN FLPDVYVPCE TCQGKRFNRE
TLEIRYKGKS IADVLDMSVN NAVEFFQSIP KIFNKVKTLR DVGLGYITLG QQSTTLSGGE
AQRVKLATEL SKRDTGKTMY ILDEPTTGLH FEDVRILMDV IDRLVNKGNS VVIIEHNMDV
IKLADHIIDV GPEGGEAGGN IVFEGTPEQI LKSKNSYTGK FLKMEIDKVH S
//
