ID G8RHB4_MYCRN Unreviewed; 516 AA.
AC G8RHB4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Acetyl-CoA carboxylase, carboxyltransferase component (Subunits alpha and beta) {ECO:0000313|EMBL:AEV74594.1};
GN OrderedLocusNames=MycrhN_4088 {ECO:0000313|EMBL:AEV74594.1};
OS Mycolicibacterium rhodesiae (strain NBB3) (Mycobacterium rhodesiae).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=710685 {ECO:0000313|EMBL:AEV74594.1, ECO:0000313|Proteomes:UP000005442};
RN [1] {ECO:0000313|EMBL:AEV74594.1, ECO:0000313|Proteomes:UP000005442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBB3 {ECO:0000313|EMBL:AEV74594.1,
RC ECO:0000313|Proteomes:UP000005442};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Gu W., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Pagani I., Mattes T., Holmes A.,
RA Rutledge P., Paulsen I., Coleman N., Woyke T.;
RT "Complete sequence of Mycobacterium rhodesiae NBB3.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AccD/PCCB family.
CC {ECO:0000256|ARBA:ARBA00006102}.
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DR EMBL; CP003169; AEV74594.1; -; Genomic_DNA.
DR RefSeq; WP_014212346.1; NC_016604.1.
DR AlphaFoldDB; G8RHB4; -.
DR STRING; 710685.MycrhN_4088; -.
DR KEGG; mrh:MycrhN_4088; -.
DR PATRIC; fig|710685.3.peg.4102; -.
DR eggNOG; COG4799; Bacteria.
DR HOGENOM; CLU_018822_0_1_11; -.
DR OrthoDB; 9803706at2; -.
DR Proteomes; UP000005442; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR InterPro; IPR034733; AcCoA_carboxyl_beta.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011763; COA_CT_C.
DR InterPro; IPR011762; COA_CT_N.
DR InterPro; IPR045190; MCCB/AccD1-like.
DR PANTHER; PTHR22855; ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED; 1.
DR PANTHER; PTHR22855:SF13; METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL; 1.
DR Pfam; PF01039; Carboxyl_trans; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
DR PROSITE; PS50989; COA_CT_CTER; 1.
DR PROSITE; PS50980; COA_CT_NTER; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005442};
KW Transferase {ECO:0000313|EMBL:AEV74594.1}.
FT DOMAIN 11..267
FT /note="CoA carboxyltransferase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50980"
FT DOMAIN 268..508
FT /note="CoA carboxyltransferase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50989"
SQ SEQUENCE 516 AA; 55481 MW; F66B68B80C4EB67C CRC64;
MTPRTSHREE HLELVAQLRD KLAAAALGGP ERARERHVGR GKLLPRDRVD GLLDPGSPFL
ELTPLAADGM YDDECPGAGM ISGIGRVSGR ECVIVANDAT VKGGTYYPIT VKKHLRAQEV
AGQNRLPCIY LVDSGGAFLP RQDEVFPDRE HFGRIFYNQA NLSAAGIPQI AAVLGSCTAG
GAYVPAMSDE AVIVRNQGTI FLGGPPLVKA ATGEIVTAED LGGGNLHSKS SGVTDHLAHD
DRDALRIVRR IVGTLGPRES LPWDVRPTVD AIADQSELYD VVPTDSRVPY DVHEVITRVI
DGGEFAEFKA EYGTTLVTGF ARIHGHPVGI VANNGVLFSE SALKGAHFIE LCDKRNTPLL
FLQNISGFMV GRDYEAGGIA KHGAKMVTAV ACARVPKLTV VIGGSYGAGN YSMCGRAYSP
RFLWMWPNAR ISVMGGEQAA SVLATVRGEM TPEEEETFKA PIRQQYEDQG NPYYSTARLW
DDGVIDPADT RTVVGLALSV VGQAPLEPVS YGVFRM
//
