ID G8RX20_MYCRN Unreviewed; 390 AA.
AC G8RX20;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Amino acid transporter {ECO:0000313|EMBL:AEV71877.1};
GN OrderedLocusNames=MycrhN_1254 {ECO:0000313|EMBL:AEV71877.1};
OS Mycolicibacterium rhodesiae (strain NBB3) (Mycobacterium rhodesiae).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=710685 {ECO:0000313|EMBL:AEV71877.1, ECO:0000313|Proteomes:UP000005442};
RN [1] {ECO:0000313|EMBL:AEV71877.1, ECO:0000313|Proteomes:UP000005442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBB3 {ECO:0000313|EMBL:AEV71877.1,
RC ECO:0000313|Proteomes:UP000005442};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Gu W., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Pagani I., Mattes T., Holmes A.,
RA Rutledge P., Paulsen I., Coleman N., Woyke T.;
RT "Complete sequence of Mycobacterium rhodesiae NBB3.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. {ECO:0000256|ARBA:ARBA00009523}.
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DR EMBL; CP003169; AEV71877.1; -; Genomic_DNA.
DR AlphaFoldDB; G8RX20; -.
DR STRING; 710685.MycrhN_1254; -.
DR KEGG; mrh:MycrhN_1254; -.
DR PATRIC; fig|710685.3.peg.1262; -.
DR eggNOG; COG0531; Bacteria.
DR HOGENOM; CLU_007946_15_12_11; -.
DR Proteomes; UP000005442; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR PANTHER; PTHR42770; AMINO ACID TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR42770:SF7; ARGININE_AGMATINE ANTIPORTER; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005442};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 63..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..338
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
SQ SEQUENCE 390 AA; 39193 MW; 2BCC317FCAA21846 CRC64;
MLGAGIFVAL APAAAAAGSG LLIGLGIAAV VAYCNATSSA RLAARYPQSG GTYVYGKERL
GEFWGYTAGW SFVVGKTASC SAMALTVGYY VWPSFAHAVA VGAVVALTAV NYAGIQRSAL
LTRVIVVAVL AVLAVVVVVI LGFGDADVGR IGIGDDASPA GVLQAAGLLF FAFAGYARIA
TLGEEVRDPA RTIPRAISIA LTIALVVYGV VAFAVLSELG SDALASATAP LADAVAAAGF
PGLEPVVRVG AAVAALGSLL ALVLGVSRTT LAMARDRHLP HALAAVHPRY GSPHRAEVTV
GVVVAVAAAV VDVRQAIGFS SFAVLLYYAI ANASAWTLGA RVVPAVGLAG CLLLAFTLPV
SSVVVGSGVV VAGMVAYGLR SWLDGHGRPR
//
