ID G8S5K3_ACTS5 Unreviewed; 1307 AA.
AC G8S5K3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:AEV86205.1};
DE EC=3.6.1.- {ECO:0000313|EMBL:AEV86205.1};
GN Name=hrpA {ECO:0000313|EMBL:AEV86205.1};
GN OrderedLocusNames=ACPL_5318 {ECO:0000313|EMBL:AEV86205.1};
OS Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=134676 {ECO:0000313|EMBL:AEV86205.1, ECO:0000313|Proteomes:UP000005440};
RN [1] {ECO:0000313|Proteomes:UP000005440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31044 / CBS 674.73 / SE50/110
RC {ECO:0000313|Proteomes:UP000005440};
RA Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K.,
RA Wehmeier U.F., Stoye J., Puehler A.;
RT "The complete genome sequence of the acarbose producer Actinoplanes sp.
RT SE50/110.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003170; AEV86205.1; -; Genomic_DNA.
DR RefSeq; WP_014692276.1; NZ_LT827010.1.
DR STRING; 134676.ACPL_5318; -.
DR KEGG; ase:ACPL_5318; -.
DR PATRIC; fig|134676.3.peg.5228; -.
DR eggNOG; COG1643; Bacteria.
DR HOGENOM; CLU_001832_3_3_11; -.
DR OrthoDB; 9805617at2; -.
DR Proteomes; UP000005440; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:AEV86205.1};
KW Hydrolase {ECO:0000313|EMBL:AEV86205.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000005440}.
FT DOMAIN 87..250
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 286..454
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 1307 AA; 146813 MW; 3228EC93DC2A4507 CRC64;
MSTSPSAPPA ELRSRITQLL PRDEHRIGRR LEGTRRIRDD AAKSAALAEI TAEVERAEAR
LASRAATVPP ITYPEALPVS ARKDDIAAAI RDHQVVVVAG ETGSGKTTQI PKICLELGRG
VRGQIGHTQP RRIAARTVAE RIAEELDRPL GATVGYKVRF TDQAGEDTLV KVMTDGILLA
EIQTDRMLRR YDTLIIDEAH ERSLNIDFIL GYLRDLLPKR PDLKLIITSA TIETQRFAEH
FADAAGQPAP VIEVSGRTYP VEVRYRPLIT TQVIDDDEIR EEPIDQIEGI AAAVDELPAD
GDILVFLSGE REIRDTADAL TRKDLRNTEV VPLYGRLSAA EQHRVFERHT GRRIVLATNV
AETSLTVPGI RYVIDPGTAR ISRYSSRLKV QRLPIEAVSQ ASANQRKGRC GRTSDGICIR
LYSEEDFDGR PEFTEPEILR TNLASVILQM TNLGLGDLAK FPFIDPPDKR NITDGIKLLE
ELGALQDRKL TPIGRQLAQL PVDPRLARMV IEADRQECVA EVMVIAAALS IQDPRERPAD
RQQQADEKHS RFTDKESDFF TYLNLWRYLR QKQQELSGNQ FRRLCRAEFL NYLRVREWQD
IYAQLRQVVR TLELNFREDW ESGVAPQPVH TALLAGLLSH IGLKDTDKRE YLGARGAKFA
IFPGSALFKR QPRWLMSAEL VETSRLWARV NARIEPEWAE KLAPHLVKHS YSEPHWDRKM
GAVMAFEKVT LYGLPIIPRR RVGYGKIDPV VARDLFIRHA LVEGDWDTHH KFFEANRQLL
RRITELENRA RRRDIAVDDE AVHALYDARI PADIVSSRHF DGWWKKARHE NPDLLTFTRE
DLVNAGRDTV DPNAFPDAWL AGGVKLPLLY EFEPNSHADG VTVRVPLDLI NKIDADDFGW
SVPGFRKDVV IALIRALPKA LRTSFVPVPD WADAVLDRVP VRRGPLPDAI AGELRRLSGT
IVPRDAWRPD QVPDHLRMNF RIVNEAGEVV AEGRDLDVLR RALAPKVQAT ISRAAGNLER
TGITTNDFGA IPHRVAQQRG GYAVTVWPAL VDEGASVGVK VFETEAEQRV AMRAGTRRLL
LLTLPPAARF LQGRLDNRAK LELSRANPYR SIADLLDDCA GAAVDRLVAD AGGPVWSSVE
FASLRDTVRE DLVDAVANVV TQVQAVLSTA YDVDQRIRQL KDPGLLPALA DIRQQLKGLV
YPGFVTETGW RQLHHLPRYL KAIAHRMDRL GGGVGRDRQL TTQIHEIETE YRELLAEAPP
GGPAAEGLRE IRWMLEELRV SFFAQSLGTA YPVSDKRIFK AMDALPL
//
