ID G8SEX8_ACTS5 Unreviewed; 502 AA.
AC G8SEX8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=cellulose synthase (UDP-forming) {ECO:0000256|ARBA:ARBA00012539};
DE EC=2.4.1.12 {ECO:0000256|ARBA:ARBA00012539};
GN OrderedLocusNames=ACPL_4538 {ECO:0000313|EMBL:AEV85429.1};
OS Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=134676 {ECO:0000313|EMBL:AEV85429.1, ECO:0000313|Proteomes:UP000005440};
RN [1] {ECO:0000313|Proteomes:UP000005440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31044 / CBS 674.73 / SE50/110
RC {ECO:0000313|Proteomes:UP000005440};
RA Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K.,
RA Wehmeier U.F., Stoye J., Puehler A.;
RT "The complete genome sequence of the acarbose producer Actinoplanes sp.
RT SE50/110.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003170; AEV85429.1; -; Genomic_DNA.
DR RefSeq; WP_014691501.1; NZ_LT827010.1.
DR AlphaFoldDB; G8SEX8; -.
DR STRING; 134676.ACPL_4538; -.
DR KEGG; ase:ACPL_4538; -.
DR PATRIC; fig|134676.3.peg.4450; -.
DR eggNOG; COG1215; Bacteria.
DR HOGENOM; CLU_542536_0_0_11; -.
DR OrthoDB; 9806824at2; -.
DR Proteomes; UP000005440; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0047259; F:glucomannan 4-beta-mannosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:UniProtKB-KW.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43867; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR PANTHER; PTHR43867:SF2; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Cellulose biosynthesis {ECO:0000256|ARBA:ARBA00022916};
KW Glycosyltransferase {ECO:0000313|EMBL:AEV85429.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005440};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AEV85429.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..500
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 156..340
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF13632"
SQ SEQUENCE 502 AA; 56060 MW; 048622DD4D73E1F0 CRC64;
MTSTILLLAV PGFLTLYFGF FAVFNYTYAF GALTRRRPPT VPLPLDAAVA VVIVSFNERE
VIADTVVACE QLTYRNKTII VGDDSTDPET IALLRTLAQE RGCTLVPGAR YAGSDIELWE
SDRFVLFHRA ENVGFKAGNL STMEQYLRQR GFSHMYLLDA DWRPQADAVE RCLEVIAADP
ATGYVQAKRL YHYGRSDHFQ RCLALNEESC YLSDLPGRQR WNHMVLFTGC CAMFDLRALY
AVGGFRAGHL TEDIDLSNRF YLSGYRGVYL EDVANLGEVP PNYQAFRRQQ ERWAIGSART
FKEYLLPVLR SGLDLRTKWS LLRQNAYYTA ALGVELSVVW SLLVVAVAVL GTGPGWPAAE
PGELLRVLGY GLGPVMLVTL LSGVAPLVVT TIKKREWINL LYIPVASWIA LSVVHTYAIA
NIKGFRNTAQ SWFVTPKTNR KKGAVRIRAG RRMRAFNMVT LVAMTATYLA VYHHTPDPAS
LALLAVYAAL WLPSMAIAAM RS
//
