ID G8SG13_ACTS5 Unreviewed; 342 AA.
AC G8SG13;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Terpene synthase {ECO:0000256|RuleBase:RU366034};
DE EC=4.2.3.- {ECO:0000256|RuleBase:RU366034};
GN OrderedLocusNames=ACPL_2023 {ECO:0000313|EMBL:AEV82920.1};
OS Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=134676 {ECO:0000313|EMBL:AEV82920.1, ECO:0000313|Proteomes:UP000005440};
RN [1] {ECO:0000313|Proteomes:UP000005440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31044 / CBS 674.73 / SE50/110
RC {ECO:0000313|Proteomes:UP000005440};
RA Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K.,
RA Wehmeier U.F., Stoye J., Puehler A.;
RT "The complete genome sequence of the acarbose producer Actinoplanes sp.
RT SE50/110.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(E)-2-methylgeranyl diphosphate + H2O = 2-methylisoborneol +
CC diphosphate; Xref=Rhea:RHEA:32571, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:61984, ChEBI:CHEBI:61987;
CC EC=4.2.3.118; Evidence={ECO:0000256|ARBA:ARBA00035573};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946,
CC ECO:0000256|RuleBase:RU366034};
CC -!- SIMILARITY: Belongs to the terpene synthase family. 2-methylisoborneol
CC synthase subfamily. {ECO:0000256|ARBA:ARBA00035653}.
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DR EMBL; CP003170; AEV82920.1; -; Genomic_DNA.
DR RefSeq; WP_014688992.1; NZ_LT827010.1.
DR AlphaFoldDB; G8SG13; -.
DR STRING; 134676.ACPL_2023; -.
DR KEGG; ase:ACPL_2023; -.
DR PATRIC; fig|134676.3.peg.1939; -.
DR eggNOG; COG3170; Bacteria.
DR HOGENOM; CLU_047127_0_0_11; -.
DR Proteomes; UP000005440; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010333; F:terpene synthase activity; IEA:InterPro.
DR GO; GO:0042214; P:terpene metabolic process; IEA:InterPro.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR047945; MIB_synthase.
DR InterPro; IPR034686; Terpene_cyclase-like_2.
DR NCBIfam; NF041167; f2_encap_cargo2; 1.
DR PANTHER; PTHR35201; TERPENE SYNTHASE; 1.
DR PANTHER; PTHR35201:SF4; TERPENE SYNTHASE; 1.
DR Pfam; PF19086; Terpene_syn_C_2; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01020; Terpene_Cyclase_Like_2; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU366034};
KW Magnesium {ECO:0000256|RuleBase:RU366034};
KW Metal-binding {ECO:0000256|RuleBase:RU366034};
KW Reference proteome {ECO:0000313|Proteomes:UP000005440}.
SQ SEQUENCE 342 AA; 37990 MW; C187836FC5E91784 CRC64;
MVSTVIASGP TGLGTSAARL FGRVDRDEPE LFCPAPLRDD RALGERVNDA VVQWAEKAGI
YPGRLDKLRG ANFGRFMMLA HPATSDPDRL LAATKCLVAE WAADDYYVDE VSLGADPMVV
GSRLANLYSV VDPASLTPRY QADFEKHHRL QPISVAFRTA MEHLAEYASV TQLARFQHQM
AILFVAWSQE ADWHANRRTP PVWEYLVQRH LNSYLPPMIL VDVLAGYELS PAEFFDPRVR
AAFTTAGNAA VLVNDLYSGR NESETDHNLP TVLVSGERLT PRAAVRRTVE IHNELMHTFV
TSAASLSASG SPQLRRFLAD TWAWLGGSRE WHATSGRYHS SN
//
