ID G8SJR6_ACTS5 Unreviewed; 420 AA.
AC G8SJR6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase {ECO:0000313|EMBL:AEV88171.1};
DE EC=1.1.1.- {ECO:0000313|EMBL:AEV88171.1};
GN OrderedLocusNames=ACPL_7291 {ECO:0000313|EMBL:AEV88171.1};
OS Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=134676 {ECO:0000313|EMBL:AEV88171.1, ECO:0000313|Proteomes:UP000005440};
RN [1] {ECO:0000313|Proteomes:UP000005440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31044 / CBS 674.73 / SE50/110
RC {ECO:0000313|Proteomes:UP000005440};
RA Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K.,
RA Wehmeier U.F., Stoye J., Puehler A.;
RT "The complete genome sequence of the acarbose producer Actinoplanes sp.
RT SE50/110.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; CP003170; AEV88171.1; -; Genomic_DNA.
DR RefSeq; WP_014694233.1; NZ_LT827010.1.
DR AlphaFoldDB; G8SJR6; -.
DR STRING; 134676.ACPL_7291; -.
DR KEGG; ase:ACPL_7291; -.
DR PATRIC; fig|134676.3.peg.7205; -.
DR eggNOG; COG0677; Bacteria.
DR HOGENOM; CLU_023810_3_2_11; -.
DR OrthoDB; 5193947at2; -.
DR Proteomes; UP000005440; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF1; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:AEV88171.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005440}.
FT DOMAIN 319..414
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 420 AA; 44983 MW; C5318436140F751D CRC64;
MSYDVVILGL GYVGLPLAQQ AIRAGMSVLG FDVDETVVKS LAAGRSHVDD LSDADVAEML
AGGFRATADE TEIATARTAV ICVPTPLSEG DGPDLRAVTG ATGSVGRNLR AGMLVVLEST
TYPGTTDDVV RPLLERLSGL TAGIDFHLAF SPERIDPGNA EYGAHNTPKV VGGYTTACTE
AAAGFYGRFI ETVVRARGTR EAETAKLLEN TYRHVNIALV NEMARFCHEL DIDLWDVINA
ASTKPFGFQA FYPGPGVGGH CIPIDPNYLS HNVRSKLGYP FRFVELAQEI NATMPAYVAR
RAQNLLNADG QAVRGATVLL LGITYKPNIA DQRESPAAPL ARQLAALGAT VSYHDPHVGT
WDIGGVPVSR TEDLEGAVAS ADLVILVQNH REYDADHLAR LAKRFFDTRG VTTGREAHRL
//
