ID G8SLP7_ACTS5 Unreviewed; 1003 AA.
AC G8SLP7;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Regulatory protein afsR {ECO:0000313|EMBL:AEV84511.1};
GN Name=afsR {ECO:0000313|EMBL:AEV84511.1};
GN OrderedLocusNames=ACPL_3616 {ECO:0000313|EMBL:AEV84511.1};
OS Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=134676 {ECO:0000313|EMBL:AEV84511.1, ECO:0000313|Proteomes:UP000005440};
RN [1] {ECO:0000313|Proteomes:UP000005440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31044 / CBS 674.73 / SE50/110
RC {ECO:0000313|Proteomes:UP000005440};
RA Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K.,
RA Wehmeier U.F., Stoye J., Puehler A.;
RT "The complete genome sequence of the acarbose producer Actinoplanes sp.
RT SE50/110.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
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DR EMBL; CP003170; AEV84511.1; -; Genomic_DNA.
DR AlphaFoldDB; G8SLP7; -.
DR STRING; 134676.ACPL_3616; -.
DR KEGG; ase:ACPL_3616; -.
DR PATRIC; fig|134676.3.peg.3531; -.
DR eggNOG; COG3629; Bacteria.
DR eggNOG; COG3903; Bacteria.
DR HOGENOM; CLU_004665_2_0_11; -.
DR Proteomes; UP000005440; Chromosome.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR10098; RAPSYN-RELATED; 1.
DR PANTHER; PTHR10098:SF106; TETRATRICOPEPTIDE REPEAT PROTEIN 28; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 2.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 6.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50005; TPR; 2.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000005440};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 1..88
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT REPEAT 714..747
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 754..787
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DNA_BIND 1..88
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 1003 AA; 107270 MW; A2E7CC27166E0689 CRC64;
MLGVVEARID GVSVDLGHAR QRCVLGVLLV EAGRPVSVDQ LVDRVWGRQA PQRAAGALYS
YLSRLRRAVA GAPEVEIRRE PGGYLLTVEP QTVDLHRFRS LMAQGRAAGA DRVAAGLFTQ
ALGLWRGDPF AGLDTPWLDG MRRTLLGERF VAELDRTDVL LRLGRHAELL PVLSAAVAEH
PLDERLAGQF MVTLYRCGRQ ADADEQYRRI RRALADELGS DPGVALRRLH EQILTADPAL
VGPVEQAIDR LMERPGEKAA DRPGEKEPPV PAQLPADVRA FTGRTGELAA LDALLVSPGG
AEPPLTVALV SGTAGVGKSA LAVRWAHRVR DAFPDGQLYI NLRGYDAEQP VAVADALAGF
LTALGVRGPE IPPGIEERAA RYRSELTGRR MLVLLDNASS VEQVRPLLPG TGSCLVLVTS
RDSLPGMVAV HGAQRVNLDL LPVPDALRLL RKLVGVRVDQ EPSAAESLAA ACARLPLALR
IAAELAADRA DVPLAELVAD LGDHRLRLDL LDAGDPRAEV RAVFSWSYRN LPEAAARLFR
LLGLHPGETV HVDAVAALTG TDPVEARRLL AVLVRASLAQ AGRGGRYGLH DLLRAYAAEL
ADRHDSEAAR RAALTGLFDH YLARSAEAMA TLYPDGAGAP GDPDAARDWI EAERPNLAVL
CTYGTAHGFH PQTIALAGTL FRYLDAGGPV AEAATITACA VSAARAIGDR DAQARALSHL
GRLHRRLGRP HEAATAYRQA LSLYAGLGDR AAEAMVQRNL GSVDWLLGDY RAAADHFQRA
LTLYGELGDG AGQADALVRL GMIDARLGDP LGATQRFEAA LQRYASLGDT FSEAYVLSLL
ARLPHRPASL DRAAARLEQS LGAVRHSGDR TAEAYVLSDL AAVHARQDRL AEAAGHLRRA
LVLHRRIGDR ASEAEALNDL GQVLRAAGDG DEARAQHAQA LGLAEEIGDR YEMARAHDGI
AAAFLDAGDP DRARPHAERA RRLFAELEVP APAGPAGGQQ VGR
//
