ID G8TFB7_NIAKG Unreviewed; 585 AA.
AC G8TFB7;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Signal peptide peptidase SppA, 67K type {ECO:0000313|EMBL:AEV97327.1};
GN OrderedLocusNames=Niako_0948 {ECO:0000313|EMBL:AEV97327.1};
OS Niastella koreensis (strain DSM 17620 / KACC 11465 / NBRC 106392 /
OS GR20-10).
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Niastella.
OX NCBI_TaxID=700598 {ECO:0000313|EMBL:AEV97327.1, ECO:0000313|Proteomes:UP000005438};
RN [1] {ECO:0000313|EMBL:AEV97327.1, ECO:0000313|Proteomes:UP000005438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17620 / KACC 11465 / NBRC 106392 / GR20-10
RC {ECO:0000313|Proteomes:UP000005438};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Davenport K.,
RA Saunders E., Detter J.C., Tapia R., Han C., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B.,
RA Pomrenke H., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Niastella koreensis GR20-10.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S49 family.
CC {ECO:0000256|ARBA:ARBA00008683}.
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DR EMBL; CP003178; AEV97327.1; -; Genomic_DNA.
DR RefSeq; WP_014217241.1; NC_016609.1.
DR AlphaFoldDB; G8TFB7; -.
DR STRING; 700598.Niako_0948; -.
DR KEGG; nko:Niako_0948; -.
DR PATRIC; fig|700598.3.peg.968; -.
DR eggNOG; COG0616; Bacteria.
DR HOGENOM; CLU_008856_1_1_10; -.
DR OrthoDB; 9764363at2; -.
DR Proteomes; UP000005438; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR CDD; cd07018; S49_SppA_67K_type; 1.
DR CDD; cd07023; S49_Sppa_N_C; 1.
DR Gene3D; 6.20.330.10; -; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR004634; Pept_S49_pIV.
DR InterPro; IPR004635; Pept_S49_SppA.
DR InterPro; IPR002142; Peptidase_S49.
DR InterPro; IPR047217; S49_SppA_67K_type_N.
DR InterPro; IPR047272; S49_SppA_C.
DR NCBIfam; TIGR00705; SppA_67K; 1.
DR NCBIfam; TIGR00706; SppA_dom; 1.
DR PANTHER; PTHR33209; PROTEASE 4; 1.
DR PANTHER; PTHR33209:SF1; SERINE PROTEASE SPPA, CHLOROPLASTIC; 1.
DR Pfam; PF01343; Peptidase_S49; 2.
DR PIRSF; PIRSF001217; Protease_4_SppA; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 121..270
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT DOMAIN 367..518
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT ACT_SITE 189
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
FT ACT_SITE 383
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
SQ SEQUENCE 585 AA; 65187 MW; 5195F6B1A9099A4E CRC64;
MKSFFKIFLA SLLAFFVLCV ILFFVFVGLI TGLTSSERVT TGSKAVLVLD LSRTYKEIGE
ENPLSRFTDK EDGDIPSLYD VMRMIRYAKS DSAVKGIYLK CGSNGNGMGA SQEIRNALID
FKSTGKFVYA YGDVITQGGY SVGNIADKIY CNPKGGVDWR GFAIQLAFLK GLLQKLEIEP
QIFYAGKFKS ATEPFRETQM TEANRLQLSV MLGDFYNRLL LQTAEARKLD TATLHQYAND
YKIRFAADAV TYKLIDGLKY DDEVKNEIAT RLGRVKLDKI NFITMQKYAK AVDFKRDGKE
KIAVIYAQGD IIDGKGDRDM IGSVTYRELF RKARLDDNIK AIVVRINSGG GSALASENMW
RELTLARKGG KPVVVSFGDV AASGAYYLSC NADSIFAQTN TITGSIGVFT MLPNLEKFFN
NKLGVTFDGV KTAPQADMLV ATKPLTPAQR TWLQNSVDST YYTFKQRVAE GRRKDISYID
SIGQGRVWSG SRALELGLVD RLGGLDDAIA CAARMAKISD YRLREYPEPH NFLEVLLGNA
EKDNTQSAIQ KEFGEEGMKT WQTMKRVKTM MGVTQARIPF EIAIQ
//
