ID G8UMU9_TANFA Unreviewed; 393 AA.
AC G8UMU9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit {ECO:0000313|EMBL:AEW20153.1};
DE EC=2.1.1.132 {ECO:0000313|EMBL:AEW20153.1};
GN Name=cbiE {ECO:0000313|EMBL:AEW20153.1};
GN OrderedLocusNames=BFO_2781 {ECO:0000313|EMBL:AEW20153.1};
OS Tannerella forsythia (strain ATCC 43037 / JCM 10827 / CCUG 21028 A / KCTC
OS 5666 / FDC 338) (Bacteroides forsythus).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC Tannerella.
OX NCBI_TaxID=203275 {ECO:0000313|EMBL:AEW20153.1, ECO:0000313|Proteomes:UP000005436};
RN [1] {ECO:0000313|Proteomes:UP000005436}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43037 / JCM 10827 / CCUG 33226 / KCTC 5666 / FDC 338
RC {ECO:0000313|Proteomes:UP000005436};
RA Dewhirst F., Tanner A., Izard J., Brinkac L., Durkin A.S., Hostetler J.,
RA Shetty J., Torralba M., Gill S., Nelson K.;
RT "Complete sequence of Tannerella forsythia ATCC 43037.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
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DR EMBL; CP003191; AEW20153.1; -; Genomic_DNA.
DR RefSeq; WP_014225904.1; NC_016610.1.
DR AlphaFoldDB; G8UMU9; -.
DR STRING; 203275.BFO_2781; -.
DR GeneID; 34759600; -.
DR KEGG; tfo:BFO_2781; -.
DR PATRIC; fig|203275.8.peg.2382; -.
DR eggNOG; COG2241; Bacteria.
DR eggNOG; COG2242; Bacteria.
DR HOGENOM; CLU_031955_1_1_10; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000005436; Chromosome.
DR GO; GO:0046025; F:precorrin-6Y C5,15-methyltransferase (decarboxylating) activity; IEA:UniProtKB-EC.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11644; Precorrin-6Y-MT; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR012818; CbiE.
DR InterPro; IPR006365; Cbl_synth_CobL.
DR InterPro; IPR014008; Cbl_synth_MTase_CbiT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR02467; CbiE; 1.
DR NCBIfam; TIGR02469; CbiT; 1.
DR PANTHER; PTHR43182; COBALT-PRECORRIN-6B C(15)-METHYLTRANSFERASE (DECARBOXYLATING); 1.
DR PANTHER; PTHR43182:SF1; COBALT-PRECORRIN-7 C(5)-METHYLTRANSFERASE; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR PIRSF; PIRSF036428; CobL; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AEW20153.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005436};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AEW20153.1}.
FT DOMAIN 62..187
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 393 AA; 44185 MW; 42100E798115731D CRC64;
MRKFYVIGIS DERRLRFPAE VERIIASGRV FSGGRRHREI VRTMLPDEAT WIDITVPLDD
VFLQYEEHQE IVVFASGDPL FFGFANTLQR VFPDAQTVTF PSFNSLQMLA HRLEMPYNEM
SVVSLTGRPW DDFDAALIKG RPLIGVLTDR EKTPPVIAAR MLEYGYDNYR MAIGERLGNE
ADERVRTMQP ADVVHGTFAA PNCLILSRTV VRSRPFGVSE KAFFLLDGRV NMITKMPVRL
LTLSMLDLRH RSSFWDIGFC TGSVSVEAKL QFPHLRITAF EKRPEGVGIL SDNCRKFGTP
GITAVTGDFM EVELHEYPTP DAVFIGGHGG RLVDILRKID ACLPPGCPIV FNSVSAASRE
MFKEGIRTIG RNVKETVCMT VDAHSPIEII KAE
//
