ID G8X1B3_STREN Unreviewed; 415 AA.
AC G8X1B3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=diacylglycerol O-acyltransferase {ECO:0000256|ARBA:ARBA00013244};
DE EC=2.3.1.20 {ECO:0000256|ARBA:ARBA00013244};
GN OrderedLocusNames=SCATT_56100 {ECO:0000313|EMBL:AEW97981.1};
OS Streptantibioticus cattleyicolor (strain ATCC 35852 / DSM 46488 / JCM 4925
OS / NBRC 14057 / NRRL 8057) (Streptomyces cattleya).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptantibioticus.
OX NCBI_TaxID=1003195 {ECO:0000313|EMBL:AEW97981.1, ECO:0000313|Proteomes:UP000007842};
RN [1] {ECO:0000313|Proteomes:UP000007842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057
RC {ECO:0000313|Proteomes:UP000007842};
RA Ou H.-Y., Li P., Zhao C., O'Hagan D., Deng Z.;
RT "Complete genome sequence of Streptomyces cattleya strain DSM 46488.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycerol + an acyl-CoA = a triacyl-sn-glycerol
CC + CoA; Xref=Rhea:RHEA:10868, ChEBI:CHEBI:17815, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:58342, ChEBI:CHEBI:64615; EC=2.3.1.20;
CC Evidence={ECO:0000256|ARBA:ARBA00001039};
CC -!- PATHWAY: Glycerolipid metabolism; triacylglycerol biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004771}.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the long-chain O-acyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009587}.
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DR EMBL; CP003219; AEW97981.1; -; Genomic_DNA.
DR AlphaFoldDB; G8X1B3; -.
DR STRING; 1003195.SCATT_56100; -.
DR KEGG; scy:SCATT_56100; -.
DR PATRIC; fig|1003195.29.peg.5592; -.
DR eggNOG; COG1020; Bacteria.
DR HOGENOM; CLU_024186_5_0_11; -.
DR UniPathway; UPA00282; -.
DR Proteomes; UP000007842; Chromosome.
DR GO; GO:0004144; F:diacylglycerol O-acyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0019432; P:triglyceride biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR045034; O-acyltransferase_WSD1-like.
DR InterPro; IPR004255; O-acyltransferase_WSD1_N.
DR PANTHER; PTHR31650:SF1; DIACYGLYCEROL O-ACYLTRANSFERASE TGS4-RELATED; 1.
DR PANTHER; PTHR31650; O-ACYLTRANSFERASE (WSD1-LIKE) FAMILY PROTEIN; 1.
DR Pfam; PF03007; WS_DGAT_cat; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000007842};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 13..161
FT /note="O-acyltransferase WSD1-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03007"
SQ SEQUENCE 415 AA; 45955 MW; C27130D264D1C01A CRC64;
MQDRLILELA RVSADTSLHL GAVLTFDGPP PGADRLAAHL EARLAGLPEL TFRLAGTARR
PRWEPDPCFD VRRQLHVYDL PDGRADDPDR VLTAMLGQPL RRDRPLWGVW LVRGAGGYAL
CYRAHHAFQD GLAAAETCER LFGPPPVVRP RRKGEVLPAV PEQRGRSRRS AVWRDLLPPV
RRTARWSPLD RPLSGERVVT TADVELARLH TIGRATGASV NQVCLAAVTA TLRAWHPADW
SGTAVRDLRA TLAINVRSAH EPYRLLGNRG GIANIALPCG EPVPLRALAE LREQVTFARL
ADLGRRHRVL YQKMPYWCGH LGLGRSIDPR YTPLTVADVR MRKPLGFAGQ PARTLHPLPV
SVPGQPLFIA WSTHRGRLHT TFLADAAVRD HRELSGRWYE AVDALESAVR AGCAP
//
