ID G8XZ82_PICSO Unreviewed; 829 AA.
AC G8XZ82;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 03-MAY-2023, entry version 58.
DE SubName: Full=Piso0_005516 protein {ECO:0000313|EMBL:CCE86991.1};
GN Name=Piso0_005516 {ECO:0000313|EMBL:CCE86991.1};
GN ORFNames=GNLVRS01_PISO0N16799g {ECO:0000313|EMBL:CCE86991.1};
OS Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC
OS 10061 / NRRL Y-12695) (Hybrid yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Millerozyma.
OX NCBI_TaxID=559304 {ECO:0000313|EMBL:CCE86991.1, ECO:0000313|Proteomes:UP000005222};
RN [1] {ECO:0000313|Proteomes:UP000005222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL
RC Y-12695 {ECO:0000313|Proteomes:UP000005222};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
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DR EMBL; FO082046; CCE86991.1; -; Genomic_DNA.
DR AlphaFoldDB; G8XZ82; -.
DR STRING; 559304.G8XZ82; -.
DR eggNOG; KOG3519; Eukaryota.
DR HOGENOM; CLU_007879_0_0_1; -.
DR InParanoid; G8XZ82; -.
DR OMA; NWRGFNL; -.
DR Proteomes; UP000005222; Chromosome N.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd05992; PB1; 1.
DR CDD; cd13246; PH_Scd1; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010481; Cdc24/Scd1_N.
DR InterPro; IPR033511; Cdc24/Scd1_PH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR47339; CELL DIVISION CONTROL PROTEIN 24; 1.
DR PANTHER; PTHR47339:SF1; CELL DIVISION CONTROL PROTEIN 24; 1.
DR Pfam; PF06395; CDC24; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF15411; PH_10; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00666; PB1; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS51745; PB1; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005222}.
FT DOMAIN 267..449
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 473..615
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 735..829
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 655..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 829 AA; 92028 MW; 980C8E34A53E0FF9 CRC64;
MMSSHTSVPH PPFRSFSSAS SVSLSGPTSS ITRIASGPIA SMNSNMNRPG SKEDQIFYQC
SRLKKRIEKI DGIEPYVKLA FEAAESCSEQ QALALSQQLS RDGSRGRNDS RASLGSLGMA
SINSNSSSVT SVGGSGSTSS IFTFTAGVLP ANIGVDPVTQ LWKLFQQGAP LCLIFNAVVS
DYTIPVVASD DMRVCKKSVY DFLIALKTHL NFDDDSMFTI SDIFSDSTHE LIKVVRTVNK
LLSISSKFGA EFDVDDLDIG QLTVSDDRSK VLKEVIETER KYVQDLELLL QYKDDLQQAE
LISSEQIHIL FPNLNEIIDF QRRFLNGLES NVNVPLKYQR IGSIFIHAAS GPFKAYEPWT
VGQLSAIDLI NKEHANLKKS SSLLDPGFEL QSYIIKPIQR LCKYPLLLKE LIKYSPQSSD
HDDTISMAYN ELLLAQSAIK EVANHVNEAQ RRSENIGYLQ SLVERVQNWR GFDVKDQGEL
LYHSAVGVRD SDSEREYTAC LFDKIIFFFI ESSGHKEKEG KKRRDILSGR KKSTGSSSST
VNLLDTLTHA KEKALLELKG RVYISEIYSI SASNILGYTL IISWSGKKES GSFTLRFANE
EVRNQWENCL RSLKSCEMNS QIHKKLAKDA HNSHVSSGTN ESSLYDLTSA YANSPSNSYT
SPANDGYSRR SSNGSQRHHS SSSTFSMMRS AVTKTSNDHV PSRVSSSSLS NPGTGFSERN
ESSFSSTSTT SEILNIGIKL IYGKIEIPEL LIVPTTISYS ELHSKISSKI ASSSEINDDI
MVNKLKYKDE DGDFVVMDSN DDWLLAVDMF DDFGAKPISY ERCLTIWVS
//
