ID G8XZR5_PICSO Unreviewed; 550 AA.
AC G8XZR5;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 22-FEB-2023, entry version 39.
DE SubName: Full=Piso0_005717 protein {ECO:0000313|EMBL:CCE87174.1};
GN Name=Piso0_005717 {ECO:0000313|EMBL:CCE87174.1};
GN ORFNames=GNLVRS01_PISO0N21045g {ECO:0000313|EMBL:CCE87174.1};
OS Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC
OS 10061 / NRRL Y-12695) (Hybrid yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Millerozyma.
OX NCBI_TaxID=559304 {ECO:0000313|EMBL:CCE87174.1, ECO:0000313|Proteomes:UP000005222};
RN [1] {ECO:0000313|Proteomes:UP000005222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL
RC Y-12695 {ECO:0000313|Proteomes:UP000005222};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
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DR EMBL; FO082046; CCE87174.1; -; Genomic_DNA.
DR AlphaFoldDB; G8XZR5; -.
DR STRING; 559304.G8XZR5; -.
DR eggNOG; KOG4406; Eukaryota.
DR HOGENOM; CLU_017277_0_0_1; -.
DR InParanoid; G8XZR5; -.
DR OMA; LIWINDW; -.
DR Proteomes; UP000005222; Chromosome N.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005222}.
FT DOMAIN 190..370
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 502..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 550 AA; 63487 MW; 9AD6315B15D8FC4C CRC64;
MERIFYKTGV VDPDTKLPVY IFDTSYLPST KVINYDRFIP TLMETLPSEK YVLIMLSCGL
NKISWIWGIK FLKTFLGDNE SNLLDKLVRI ITVHDSWFVK TITEIFKNYS ITRKNFSLLN
KLMESFNLIS DFDMGTSNFN TIRHCANLAE LHRCIDVTKL KISLNVYKYD CQLGNDLDLL
DKTPILNQNT QIDPVSEPSF FHHFYQIFNI IDSYGDKSEL VFHRPGNKLS TDILFKCVVR
NSVFWINDWD IFCIATTFKK ILMELPHPFI SIDLIELPVK DDINYTKRNL DNILFSYQGK
TNYRQVLLQI CDLCQNLMNN RAVTKHTSST LAKCLSHCLS QELVSLQNKD NILVISRFIK
NLLDFWHQIR GSYSRSYQSI KEIVEGDLPD EVSHSYEVSY DVTIEEDENE RVLANTSNIL
SMNHDLINES DERGSVASDE SLAKTLVSRE ASRESFVDQL EQKDDFFPSY NEKQSSSSTD
RSTLSDLTNI GIQYPPQKYK FQAKPAVTPS RTESVQPPTG KKPVIRGRKV GELARLFEER
AQGIDLLKSM
//
