ID G8Y3X2_PICSO Unreviewed; 518 AA.
AC G8Y3X2;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Piso0_004986 protein {ECO:0000313|EMBL:CCE85390.1};
GN Name=Piso0_004986 {ECO:0000313|EMBL:CCE85390.1};
GN ORFNames=GNLVRS01_PISO0M05226g {ECO:0000313|EMBL:CCE85390.1};
OS Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC
OS 10061 / NRRL Y-12695) (Hybrid yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Millerozyma.
OX NCBI_TaxID=559304 {ECO:0000313|EMBL:CCE85390.1, ECO:0000313|Proteomes:UP000005222};
RN [1] {ECO:0000313|Proteomes:UP000005222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL
RC Y-12695 {ECO:0000313|Proteomes:UP000005222};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. TrmE GTPase family. {ECO:0000256|ARBA:ARBA00011043,
CC ECO:0000256|RuleBase:RU003313}.
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DR EMBL; FO082047; CCE85390.1; -; Genomic_DNA.
DR AlphaFoldDB; G8Y3X2; -.
DR STRING; 559304.G8Y3X2; -.
DR eggNOG; KOG1191; Eukaryota.
DR HOGENOM; CLU_019624_3_1_1; -.
DR InParanoid; G8Y3X2; -.
DR OMA; FALCTPW; -.
DR Proteomes; UP000005222; Chromosome M.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006400; P:tRNA modification; IEA:InterPro.
DR CDD; cd04164; trmE; 1.
DR CDD; cd14858; TrmE_N; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.120.430; tRNA modification GTPase MnmE domain 2; 1.
DR HAMAP; MF_00379; GTPase_MnmE; 1.
DR InterPro; IPR031168; G_TrmE.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR018948; GTP-bd_TrmE_N.
DR InterPro; IPR004520; GTPase_MnmE.
DR InterPro; IPR027368; MnmE_dom2.
DR InterPro; IPR025867; MnmE_helical.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR00450; mnmE_trmE_thdF; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42714; TRNA MODIFICATION GTPASE GTPBP3; 1.
DR PANTHER; PTHR42714:SF2; TRNA MODIFICATION GTPASE GTPBP3, MITOCHONDRIAL; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR Pfam; PF12631; MnmE_helical; 1.
DR Pfam; PF10396; TrmE_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003313};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003313};
KW Reference proteome {ECO:0000313|Proteomes:UP000005222};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694,
KW ECO:0000256|RuleBase:RU003313}.
FT DOMAIN 44..167
FT /note="GTP-binding protein TrmE N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10396"
FT DOMAIN 170..515
FT /note="MnmE helical"
FT /evidence="ECO:0000259|Pfam:PF12631"
FT DOMAIN 270..387
FT /note="G"
FT /evidence="ECO:0000259|Pfam:PF01926"
SQ SEQUENCE 518 AA; 57340 MW; A59B685478745D67 CRC64;
MLTFMLGGKG SWGSRIFLGL SRISTNSRSF NGTRSFSDLV QNPTIYALST HLTRSAIGVI
RISGSQSKYI LDCLTGKKCV AKHRMTSVRK LYSPKDKTLI DEALTIFFKS PGSYTGEDML
ELHLHGGTAL VQTALRNIQS LHDPSRQIYI RYAENGEFSR RAFMNGRFDL TELEGIREMI
DAETESQRLA ALTSMKGETR SLFSSWREEI VKNIAMLTTI IDFGEDHDIE EVDKIFQGVS
DSIDGLRDEI LRYLERVTGS EVLLKGIKLT FLGPPNAGKS SLLNYLSDKD MVIVSDIAGT
TRDAIDVPIN INGYKVILGD TAGIRSSSDV GTIEFEGIKR AKMKSLSGDI ILVVLPIDER
LQDHTELVQH ISSLKEENKR ILIVLNKIDL LQSNGSLDEV KTLHAEALGL SNDNIFTVSC
VTSEGTKELT SALTSYFKEI SKTTQNDPVI ISTRAQDLLK NDVLYGFEQF KFYKDQSDVV
LATESLKQSV DGIAKVTGEA VGVEEILGVV FSKFCIGK
//
