ID G8Y8P3_PICSO Unreviewed; 668 AA.
AC G8Y8P3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Piso0_004396 protein {ECO:0000313|EMBL:CCE83807.1};
GN Name=Piso0_004396 {ECO:0000313|EMBL:CCE83807.1};
GN ORFNames=GNLVRS01_PISO0K15960g {ECO:0000313|EMBL:CCE83807.1},
GN GNLVRS01_PISO0L15961g {ECO:0000313|EMBL:CCE84838.1};
OS Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC
OS 10061 / NRRL Y-12695) (Hybrid yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Millerozyma.
OX NCBI_TaxID=559304 {ECO:0000313|EMBL:CCE83807.1, ECO:0000313|Proteomes:UP000005222};
RN [1] {ECO:0000313|EMBL:CCE83807.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000005222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL
RC Y-12695 {ECO:0000313|Proteomes:UP000005222};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
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DR EMBL; FO082049; CCE83807.1; -; Genomic_DNA.
DR EMBL; FO082048; CCE84838.1; -; Genomic_DNA.
DR AlphaFoldDB; G8Y8P3; -.
DR STRING; 559304.G8Y8P3; -.
DR eggNOG; KOG3671; Eukaryota.
DR HOGENOM; CLU_015385_1_2_1; -.
DR InParanoid; G8Y8P3; -.
DR OMA; PPNDECY; -.
DR Proteomes; UP000005222; Chromosome K.
DR Proteomes; UP000005222; Chromosome L.
DR GO; GO:0005769; C:early endosome; IEA:InterPro.
DR GO; GO:0071203; C:WASH complex; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0043014; F:alpha-tubulin binding; IEA:InterPro.
DR GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IEA:InterPro.
DR CDD; cd01205; EVH1_WASP-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR028290; WASH1.
DR InterPro; IPR033927; WASPfam_EVH1.
DR InterPro; IPR000697; WH1/EVH1_dom.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR23331; CXYORF1; 1.
DR PANTHER; PTHR23331:SF1; WASH COMPLEX SUBUNIT 1; 1.
DR Pfam; PF00568; WH1; 1.
DR Pfam; PF02205; WH2; 1.
DR SMART; SM00461; WH1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50229; WH1; 1.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005222}.
FT DOMAIN 17..128
FT /note="WH1"
FT /evidence="ECO:0000259|PROSITE:PS50229"
FT DOMAIN 584..603
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 216..668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..344
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..393
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..436
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..459
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 490..504
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..581
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 668 AA; 71357 MW; 205B1F3937728EAB CRC64;
MGGLLNSSDK EKIKRAIPKA NNKLIDATVA RLYIAYPEPT RWQYTNLMGA IILADDLVGH
TFFLKLVDII GHRGVIWDQE LYVDFQYHQD RTFFHTFELE DCWAGLLFED TSEASHFYKR
VVNRHKYGSK QTVNNKNAIA LKENVKSDTH KVGPRGEYVD VNTEQRMRRS KGVLYYDDVP
PPEWRSLYSE LEAAGITEDM IADNREFIKD YIAKRGGPLV GLEPPIPRRL KRNKSQLQRQ
ATSETTESKP SSHKNKKAPP PPPPPVVSRS STQASDSHTD VSSTNSDHLG PSDSPSSSSQ
SPFTSNANLE ESHNLRFRLP PKDAVPPSVP HSTLPPPPPV QNSPHQMPNS SIPTGNQPQR
SFSSNSQQNR PLPPPPPARG NQAPPPPARG MPPTLPQRTG ADSNQRPGGV PPPPPPRAAR
GNAPPPPPPR TQRPGVSSVP PPSSFNGMNG NQANHAQSHS SPPPLPPAHP AAGINYPNSQ
NQVNSPPAAH PAHAAPPPLP PQHTNFASPQ AQVSSPPPPP PLPQGARNDS HNAPPPPPPP
PAPPASTAPS SSAGPPPPPP LPPSDSLDTE SSGPPPPLPA TDSSRDALLS SIRSAGIGSL
KKVDKSQLDK PSVILQEAKG DTSAGGSGSG DNPPPGQPGS LADALASALH KRKGKVAGSD
DEDDGDDW
//
