ID   G8YKW3_PICSO            Unreviewed;       567 AA.
AC   G8YKW3;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Piso0_001474 protein {ECO:0000313|EMBL:CCE88697.1};
GN   Name=Piso0_001474 {ECO:0000313|EMBL:CCE88697.1};
GN   ORFNames=GNLVRS01_PISO0F07199g {ECO:0000313|EMBL:CCE88697.1};
OS   Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC
OS   10061 / NRRL Y-12695) (Hybrid yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Millerozyma.
OX   NCBI_TaxID=559304 {ECO:0000313|EMBL:CCE88697.1, ECO:0000313|Proteomes:UP000005222};
RN   [1] {ECO:0000313|Proteomes:UP000005222}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL
RC   Y-12695 {ECO:0000313|Proteomes:UP000005222};
RX   DOI=10.1534/g3.111.000745;
RA   Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA   Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA   Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA   Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA   Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA   Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA   Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA   Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT   "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT   genome resolution following polyploidization.";
RL   G3 (Bethesda) 2:299-311(2012).
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DR   EMBL; FO082054; CCE88697.1; -; Genomic_DNA.
DR   AlphaFoldDB; G8YKW3; -.
DR   STRING; 559304.G8YKW3; -.
DR   eggNOG; ENOG502QQW9; Eukaryota.
DR   HOGENOM; CLU_028296_1_0_1; -.
DR   InParanoid; G8YKW3; -.
DR   OMA; WGKWQRE; -.
DR   Proteomes; UP000005222; Chromosome F.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR019431; DUF2417.
DR   PANTHER; PTHR43139:SF60; AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43139; SI:DKEY-122A22.2; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   Pfam; PF10329; DUF2417; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005222};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        86..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        124..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        174..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        220..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          292..418
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
FT   REGION          1..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..67
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   567 AA;  64974 MW;  7D2181232090AA09 CRC64;
     MSGSNEAVSR EGEIYNSRLA EVRENSSNQE PEEHNADGTI SDTPPTSDLE RQPLLNDHER
     PRRLLSPDDA RVSPLNLHKI RLLKSVLTVI NAINGVLLFV CVLDDFISVP GFGIRGRSPL
     ELDLILICIV TNLVTLWCFA VPAYYERMLG YVCSALMGID LFLVLIVGPM RKQFSLPGII
     ILVWTFGNIL LNCFADYWVE KGRLHQEIKY TGRAETRRTI SELFVMFVKI VMKFALFLII
     WNISLFIWLQ TFDTHEKPWG KLVPVDNNSY RVHLSCYGDV HKKLGEGNDS QPIVLIEGGQ
     HTSSEEFQEW VEELYHLNKL DRYCIWDRPG YGFSDSAPSP ISIGIVSEVL TEALLRENIE
     GPFAVVGFDI GGLYARMFAS RNTGRVHSLL LVDSWHEDLL KQRPFSRPNF KNENKKVFRN
     ILEFMDVKTG FKVWLKGLVS PLGVIPNVHW FFHPKRHSSN NRIFGSDMRY MPKYLRARLQ
     EQVSSSILSY SEVVSSNIES VPVSVISSDN MIKRSLNWGK WQRELTRLSS KTTEWIVAEN
     SDHFIWRSPR GREQLQSLLL RLIGAES
//