ID G8YLM8_PICSO Unreviewed; 971 AA.
AC G8YLM8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Piso0_001756 protein {ECO:0000313|EMBL:CCE88962.1};
GN Name=Piso0_001756 {ECO:0000313|EMBL:CCE88962.1};
GN ORFNames=GNLVRS01_PISO0F13381g {ECO:0000313|EMBL:CCE88962.1};
OS Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC
OS 10061 / NRRL Y-12695) (Hybrid yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Millerozyma.
OX NCBI_TaxID=559304 {ECO:0000313|EMBL:CCE88962.1, ECO:0000313|Proteomes:UP000005222};
RN [1] {ECO:0000313|Proteomes:UP000005222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL
RC Y-12695 {ECO:0000313|Proteomes:UP000005222};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
CC {ECO:0000256|ARBA:ARBA00008334}.
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DR EMBL; FO082054; CCE88962.1; -; Genomic_DNA.
DR AlphaFoldDB; G8YLM8; -.
DR STRING; 559304.G8YLM8; -.
DR eggNOG; KOG1984; Eukaryota.
DR HOGENOM; CLU_004589_1_0_1; -.
DR InParanoid; G8YLM8; -.
DR OMA; INPFMTF; -.
DR Proteomes; UP000005222; Chromosome F.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 1.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 1.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR006895; Znf_Sec23_Sec24.
DR InterPro; IPR036174; Znf_Sec23_Sec24_sf.
DR PANTHER; PTHR13803; SEC24-RELATED PROTEIN; 1.
DR PANTHER; PTHR13803:SF4; SECRETORY 24CD, ISOFORM C; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR Pfam; PF04810; zf-Sec23_Sec24; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR SUPFAM; SSF82919; Zn-finger domain of Sec23/24; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000005222};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 222..260
FT /note="Zinc finger Sec23/Sec24-type"
FT /evidence="ECO:0000259|Pfam:PF04810"
FT DOMAIN 305..551
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 560..652
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 664..768
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 41..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 971 AA; 107292 MW; 04F77ED9CAF6F963 CRC64;
MFGGVGNEQA GQPMPPAGYN MGETGLEGAV EDMSLNSNIG GGAVRAKKKR PARAFHGGLG
TPQPYSEAGS TSEAIDSSAA HNDALLGPAG LGQPTPEPQN GQSAQESISL AQSRYMDQSE
FMSPVSDEDN SYRSFFTFQN IVPPSAGTQF HTVDQGTSSS KFMRATMYNA PETDQLRSAT
KLPVSVTIRP FAPLLPTEDP IPEVDMSDLG NTPGADPLEI GPPRCRRCRT YMNPAMQHNS
SYRFVCNICQ FPNNTIPEDY VSMINPVTGT RTDANVRPEL HRGVYDLLVP KHYNAKGPES
KNHGLHHVFL VDISEQSIKQ NVPALFADTL RAMLYNHNND DEDSSNTKSN MFEGKLAIIA
YDKRLHFFNL SPSLNKAQIA ISSDLDDPFV PFEEGLFVDP QESQLVIEDV LNHLEMLTVD
GMITEPESCF AVACRTAMMC LESVGGGKVT SVLSGLPSWG PGGLKFKDNA AVGRSLTGEQ
EMKVLNADNE YYHSLAKDFI DKFVGLDCLV ISPTSVDLSN VGWLCSVTGG SVHKWPNFNF
ERDGPAFMAK LISSACKVRG YQAQLKLRCS NGLQISQYYG TSSSITHTNI LGSANQDPII
PVVNEDQSFT VLLEYDGKLE TKFDCHFQAA LLYTDNHGRR KVRVINLVIA VSETLENIFS
FVEQDAVVTT IARDTLSFVG KQTLSELRLS INEKLVDVFT QYRAMCEFHH HNYSLNNQLL
FPDSLKHFPL YMLALIKTKA LRGSTSTSAD VRLESIFQMI NMPVERLMFY LYPGLVELHS
LNPDDGTIPE PQDGNHDGFI KLPKFKDLTS KSLDFGVYLL CNGVTVYVWV HPNANELLIQ
DLFGNVNSVE DIDPLISRLP ELPTHISLQA RNIVKYFHSN ILGTPNGLEY IQIVRPGIDG
SEVQFNECLI EDNVGKTFSA CNGPAYPEYL TNLHKAIRVK LENDKSSNNI KKAFNSIDNS
NDTLAQRLIH F
//
