ID   G8YLZ3_PICSO            Unreviewed;       634 AA.
AC   G8YLZ3;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   28-JUN-2023, entry version 43.
DE   RecName: Full=U3 small nucleolar ribonucleoprotein protein MPP10 {ECO:0000256|PIRNR:PIRNR017300};
GN   Name=Piso0_001892 {ECO:0000313|EMBL:CCE88389.1};
GN   ORFNames=GNLVRS01_PISO0F00181g {ECO:0000313|EMBL:CCE88389.1};
OS   Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC
OS   10061 / NRRL Y-12695) (Hybrid yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Millerozyma.
OX   NCBI_TaxID=559304 {ECO:0000313|EMBL:CCE88389.1, ECO:0000313|Proteomes:UP000005222};
RN   [1] {ECO:0000313|Proteomes:UP000005222}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL
RC   Y-12695 {ECO:0000313|Proteomes:UP000005222};
RX   DOI=10.1534/g3.111.000745;
RA   Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA   Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA   Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA   Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA   Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA   Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA   Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA   Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT   "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT   genome resolution following polyploidization.";
RL   G3 (Bethesda) 2:299-311(2012).
CC   -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC       {ECO:0000256|PIRNR:PIRNR017300}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|PIRNR:PIRNR017300}.
CC   -!- SIMILARITY: Belongs to the MPP10 family.
CC       {ECO:0000256|ARBA:ARBA00029455, ECO:0000256|PIRNR:PIRNR017300}.
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DR   EMBL; FO082054; CCE88389.1; -; Genomic_DNA.
DR   AlphaFoldDB; G8YLZ3; -.
DR   STRING; 559304.G8YLZ3; -.
DR   eggNOG; KOG2600; Eukaryota.
DR   HOGENOM; CLU_011271_1_0_1; -.
DR   InParanoid; G8YLZ3; -.
DR   OMA; THFEYKP; -.
DR   Proteomes; UP000005222; Chromosome F.
DR   GO; GO:0034457; C:Mpp10 complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005732; C:sno(s)RNA-containing ribonucleoprotein complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR012173; Mpp10.
DR   PANTHER; PTHR17039; U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10; 1.
DR   PANTHER; PTHR17039:SF0; U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10; 1.
DR   Pfam; PF04006; Mpp10; 1.
DR   PIRSF; PIRSF017300; snoRNP_Mpp10; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR017300};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005222};
KW   Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW   ECO:0000256|PIRNR:PIRNR017300};
KW   Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW   ECO:0000256|PIRNR:PIRNR017300};
KW   rRNA processing {ECO:0000256|ARBA:ARBA00022552,
KW   ECO:0000256|PIRNR:PIRNR017300}.
FT   REGION          100..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          216..330
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          609..634
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        103..126
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        140..161
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        162..177
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        220..245
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        246..275
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        289..316
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   634 AA;  72451 MW;  AD04DF74620C5232 CRC64;
     MPEDILKTLS SNPQNVFSLF PSESNQNENY FNKLTKEFLD PLSKDHSILE QIHIDGLDST
     QVFGQAKIVL DNVADQLLFS DIPKHASHKG DDINVKQYDE ADSEDFSESE SDADNINDEE
     QVENQSDVSE EHDGSDDFSE AGVSEDEEEE EEEDADDKYP DSDDSTENAK NDEESNVDQE
     SGDANDNSEG FNKDAFGLND GFFDIDKFNE QILDMEKSAN ADDEEIDYFE DLDEKDDEDD
     EIAYYEDFFD RPNKQDVSSK QKKDADNKFD LSDNSQSEGE GEDEDEEYNY AISSARKDLF
     DDDMSEDDDK ESQKPVNMSS FEKQQQQIQE EISKLESDLV AEKKWTMKGE VSAKSRPQDS
     LLEDPEAVDL EFDRASKPVP IVTEDFSESI DDVIRRRIKE EQFDDLPKRY ISDLEKHDRR
     PAFELSQEKS KKTLADIYEE EYNGTEDNTK SEETEKLHSE IGNLFEKVTY MLDSLCSAHY
     IPKPHQTKTI EIKASDAAEI NLEDSQPAVV GSGSTLAPQE IYSLKNKGNE NKAANQIQLK
     SGLSYSKDEL SREEKLRLRR ANKRKRSKEH KHKAELREQL AKEVPEHKRQ KRDTMDTLAA
     AKNVTVIDKK GKKRDVKGNL KKDALPHESS ILKL
//