ID G8YSE9_PICSO Unreviewed; 397 AA.
AC G8YSE9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Piso0_001109 protein {ECO:0000313|EMBL:CCE78486.1};
GN Name=Piso0_001109 {ECO:0000313|EMBL:CCE78486.1};
GN ORFNames=GNLVRS01_PISO0C11090g {ECO:0000313|EMBL:CCE78486.1},
GN GNLVRS01_PISO0D11157g {ECO:0000313|EMBL:CCE79072.1};
OS Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC
OS 10061 / NRRL Y-12695) (Hybrid yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Millerozyma.
OX NCBI_TaxID=559304 {ECO:0000313|EMBL:CCE78486.1, ECO:0000313|Proteomes:UP000005222};
RN [1] {ECO:0000313|EMBL:CCE78486.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000005222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL
RC Y-12695 {ECO:0000313|Proteomes:UP000005222};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the cation diffusion facilitator (CDF)
CC transporter (TC 2.A.4) family. SLC30A subfamily.
CC {ECO:0000256|ARBA:ARBA00008873}.
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DR EMBL; FO082057; CCE78486.1; -; Genomic_DNA.
DR EMBL; FO082056; CCE79072.1; -; Genomic_DNA.
DR AlphaFoldDB; G8YSE9; -.
DR STRING; 559304.G8YSE9; -.
DR eggNOG; KOG1483; Eukaryota.
DR HOGENOM; CLU_013430_4_3_1; -.
DR InParanoid; G8YSE9; -.
DR OMA; FQDCASW; -.
DR Proteomes; UP000005222; Chromosome C.
DR Proteomes; UP000005222; Chromosome D.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0098771; P:inorganic ion homeostasis; IEA:UniProt.
DR GO; GO:0030003; P:intracellular monoatomic cation homeostasis; IEA:UniProt.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR NCBIfam; TIGR01297; CDF; 1.
DR PANTHER; PTHR45820; FI23527P1; 1.
DR PANTHER; PTHR45820:SF4; FI23527P1; 1.
DR Pfam; PF01545; Cation_efflux; 1.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005222};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 136..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..162
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 397 AA; 44258 MW; 5FC4BA95C721D6AD CRC64;
MNSKEIRILS LLALDTVFFL LEVIIGYSVH SLALVADSFH MLNDIISLVI ALWAVRYKNT
KPADRYYTYG WQRAEILGAL INAVFLIALC FTIVIDAIQR FFEPQEISQP KLVLVVGIAG
LFSNGIGMVL FHEHGHSHSH GGGSGHDHKH GSDREEEEDI GMQHGNASST DIRSYFPESI
VERYNENSPL ISQQDKATVK RKSMNMEGVF LHALGDALGN VGVIITALFI WKTDYSWKYY
TDPLVSLILT VIIFSSALPL CRKSSKVLLQ ATPGHVNTNL VLKDITRLDL VKSVHDFHIW
NLNEDISIAS LHIELNTASN EGTSADVDNN KSINKTEFLK VVTQVREILH AYGVHSATIQ
PEFSAGPISR KPSYYGRTNQ DSCLFDSTSK CDSHQCL
//
