ID G8YSZ6_PICSO Unreviewed; 634 AA.
AC G8YSZ6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Piso0_000058 protein {ECO:0000313|EMBL:CCE73047.1};
GN Name=Piso0_000058 {ECO:0000313|EMBL:CCE73047.1};
GN ORFNames=GNLVRS01_PISO0B01277g {ECO:0000313|EMBL:CCE73047.1};
OS Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC
OS 10061 / NRRL Y-12695) (Hybrid yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Millerozyma.
OX NCBI_TaxID=559304 {ECO:0000313|EMBL:CCE73047.1, ECO:0000313|Proteomes:UP000005222};
RN [1] {ECO:0000313|Proteomes:UP000005222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL
RC Y-12695 {ECO:0000313|Proteomes:UP000005222};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FO082058; CCE73047.1; -; Genomic_DNA.
DR AlphaFoldDB; G8YSZ6; -.
DR STRING; 559304.G8YSZ6; -.
DR eggNOG; KOG1155; Eukaryota.
DR HOGENOM; CLU_018320_2_1_1; -.
DR InParanoid; G8YSZ6; -.
DR OMA; RTEHENA; -.
DR Proteomes; UP000005222; Chromosome B.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR007192; APC8.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR PANTHER; PTHR12558:SF10; CELL DIVISION CYCLE PROTEIN 23 HOMOLOG; 1.
DR Pfam; PF04049; ANAPC8; 1.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13414; TPR_11; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 3.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000005222};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT DOMAIN 58..333
FT /note="Cdc23"
FT /evidence="ECO:0000259|Pfam:PF04049"
FT REPEAT 429..462
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 463..496
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 497..530
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 634 AA; 74072 MW; 65F82E4BC6F4BC5F CRC64;
MCNQKIKIIS RSRTTLIHFV LVNKKYYTLI YLSREHHNVY KAIRAEMQED KGDQIERLRI
KLHQACRILS NLNLFQAAKW SAEALNGLPP RSGKDAANFE YPALELDQHE KEDEAKFFLA
KTYFNCKEFQ RAAYVLKDCK SGNALFFRLY SMLISIDKTT TEETDGSINI SSLSLMNNSD
IADSMDANTV TSKDEVLGSL NTKLSKIVQE SENYHSKAEN KPNAFLYYLN GVIYNKKKKY
GMAQNNLYQS LRIFPYNWSC WQELITSLNS LDEAISFINK LKAAKSSLTN NVMFHFFEIV
ILQEFYQQSA SMTTSLNNLT EMFPNFNFLK IQQFLMAYHS LDYYQAESLF DQILTDDPLR
LDDLDTYSNM LYVMEKKPKL SYLAQYAASI DKFRPETCCI IANYHSMKCE HEKAIMYYKR
ALTLNKNCLS AWTLMGHEFV ELKNSHAAIE SYRRAVDINP KDFRAWYGLG QAYEVLDMHL
YALYYYQKAT SLQPFDKRMW QAIGNCYEKI NKYEEAIKSF EKALTIDNYN RGDSESENIY
LYDPHICFKL AIICEKLRNA KDTYKYMKLC FDQEFEWGIS DETSKARLWL ARTALEGGKF
EEAYELVKDF GHNNAQDIEE ARSIAREARN RMSK
//
