ID G8YT27_PICSO Unreviewed; 1270 AA.
AC G8YT27;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Piso0_000092 protein {ECO:0000313|EMBL:CCE73078.1};
GN Name=Piso0_000092 {ECO:0000313|EMBL:CCE73078.1};
GN ORFNames=GNLVRS01_PISO0B02003g {ECO:0000313|EMBL:CCE73078.1};
OS Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC
OS 10061 / NRRL Y-12695) (Hybrid yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Millerozyma.
OX NCBI_TaxID=559304 {ECO:0000313|EMBL:CCE73078.1, ECO:0000313|Proteomes:UP000005222};
RN [1] {ECO:0000313|Proteomes:UP000005222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL
RC Y-12695 {ECO:0000313|Proteomes:UP000005222};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
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DR EMBL; FO082058; CCE73078.1; -; Genomic_DNA.
DR AlphaFoldDB; G8YT27; -.
DR STRING; 559304.G8YT27; -.
DR eggNOG; KOG2102; Eukaryota.
DR HOGENOM; CLU_002333_0_3_1; -.
DR InParanoid; G8YT27; -.
DR OMA; DDVWGSK; -.
DR Proteomes; UP000005222; Chromosome B.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR Gene3D; 2.40.50.690; -; 1.
DR Gene3D; 2.40.50.700; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR041505; Dis3_CSD2.
DR InterPro; IPR041093; Dis3l2_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR001900; RNase_II/R.
DR PANTHER; PTHR23355:SF9; DIS3-LIKE EXONUCLEASE 2; 1.
DR PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR Pfam; PF17877; Dis3l2_C_term; 1.
DR Pfam; PF17849; OB_Dis3; 1.
DR Pfam; PF00773; RNB; 1.
DR SMART; SM00955; RNB; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005222}.
FT DOMAIN 662..993
FT /note="Ribonuclease II/R"
FT /evidence="ECO:0000259|SMART:SM00955"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 74..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 155..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 406..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1167..1207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 222..244
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..322
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..476
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1270 AA; 141855 MW; 025E2985F5FAA1B0 CRC64;
MSSYNGNDQG GGFNNLNLPG FEVGGDASPG NRKPKPNIHI AHRRSPSELT TLMMEQYNLQ
RQLEAVQAQQ KQLMQQQSFS SQQPGYSPKG NFNNPDLLND FTPPQSSYKT HSRSSSINSN
TGAGNRGTGS ASNNPVGHSR RHSLGLHEAI KAAANQRQTN RTTAGSATNS STNSNDSDSI
GLYKFPAGSG SDNESITPPH SVGANLGHNR SRSLAYGQQS FKFPEDNSLM PPTPNFTINP
SPERGHQRRS SHYKSASRNF DSNNTGNINT NWRSQQQHQR LPSSLEPPST NFVPGHRHRN
SSYGGGSISS LSQFMPNNGN NQNGRKSLFA PYLPQSSLPE LINEGRLVIG VLRVNKKNRS
DAYVSTDGLL DADIFICGSK DRNRALEGDL VAVELLVVDE VWDSKKEKEE KKRRKDNNYN
KTPSSALIND DIHNDATFTA TAPAVENEEK PDNENEHGVM RRGSLKQRPT MKKNDDVEVE
GQSLLLVEEE QINDEVKPLY AGHIVAVVDR IPGQLFAGTL GLLRPSQAAQ VAKDKKSGKE
SSFQEPKAPK IVWFKPIDKK VPLIAIPTEQ APKDFVENHE HYADQLFLAS IKRWPITSLH
PFGTLISQIG KINEPETEIL SILRDNNFSC DEYPEETDAE SSWNPYLSDI PDVEIEMNLS
GRMEYLNDYV ISFTQNGGFI DHALHVKRLS NTKIELGFHV ADISFYIKPG TLLDRKAKKR
SSSVFLPQRS SHLYPEKVNS LASFKENERN LAFSVVFEID TTTFEVEDLY IHESIIAPKQ
LVSYEEFDKI IYGKPSSNIS SATSDYIQTF ALIAKEFRRQ RLNDRRLGIF PNLTLLSEVD
DEKVHLHLNI FDETPSFAII SEISHKVNSA IATKVHASLG NEAFLRRHSL PTLQKMENVV
RKAANLNIKI DTTDSASLQK SILQIENPVK RLCVETILYK CMTRGKYYVA GKQDPDSYFH
YYLNLPLYTH FNAPLRRYAD LIVHRQLKSI IKRTADPRPV DLDALKATAE YCNFKKDCAA
NAQEQAIHLL LSQTINELSG DAGQLLCMGT VLQVYESSFD VFIPELGVEK RVHGDQLPLV
KAEFDKFSRV LELYWEKGVD SATYIPPDER SSLSYRSSVK NKYRTSSSEA AKIQSKTILE
KNNLEAITEK LLSMNLDLPQ LSIPTLSKTA GNQRDANTKS MPSSPIKTDF PKNLRTNSSS
IIGTDTEGNT NEVDVVGGLK PYLSNLTTRV EDGSYIQEIR ELTQVPVLLR AEIGMALPCL
TVRVLNPFLD
//
