ID G9EJG7_9GAMM Unreviewed; 1983 AA.
AC G9EJG7;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=LDG_5330 {ECO:0000313|EMBL:EHL32733.1};
OS Legionella drancourtii LLAP12.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=658187 {ECO:0000313|EMBL:EHL32733.1, ECO:0000313|Proteomes:UP000002770};
RN [1] {ECO:0000313|EMBL:EHL32733.1, ECO:0000313|Proteomes:UP000002770}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LLAP12 {ECO:0000313|EMBL:EHL32733.1,
RC ECO:0000313|Proteomes:UP000002770};
RX PubMed=22047552; DOI=10.1186/1471-2164-12-542;
RA Gimenez G., Bertelli C., Moliner C., Robert C., Raoult D., Fournier P.E.,
RA Greub G.;
RT "Insight into cross-talk between intra-amoebal pathogens.";
RL BMC Genomics 12:542-542(2011).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
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DR EMBL; JH413796; EHL32733.1; -; Genomic_DNA.
DR RefSeq; WP_006869314.1; NZ_JH413796.1.
DR STRING; 658187.LDG_5330; -.
DR eggNOG; COG1020; Bacteria.
DR HOGENOM; CLU_234227_0_0_6; -.
DR InParanoid; G9EJG7; -.
DR OrthoDB; 9757559at2; -.
DR Proteomes; UP000002770; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR010037; FkbH_domain.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR010033; HAD_SF_ppase_IIIC.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR001031; Thioesterase.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR NCBIfam; TIGR01686; FkbH; 1.
DR NCBIfam; TIGR01681; HAD-SF-IIIC; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR SUPFAM; SSF56784; HAD-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002770}.
FT DOMAIN 583..659
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1646..1723
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT COILED 556..583
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1983 AA; 226912 MW; 7A17A58BD8016BAF CRC64;
MIHIASTYIA DVLSSSLNII LQKFCDQQVC FHYNQIFQQA LLPNSEFNEN INGLNVILIR
GADLFSPGKD NNRMITDLAI ALNSLQKTMR VPLLILFTPT QTSTIEEKKY YSTLENNLKL
AIEPNVNTTF VSSEEMQTLS KLPLLFDNLT EKYGHIPYTM NFYDSLAIFI ARKYSLLTRK
PYKVIVLDCD GTLWNGIIEE DGIDGLAING EYLALQQFMV GLFRAGFLLC LCSKNSEESV
LNVFKERKEM ALDIDKHICS YRINWLPKSA NIQSLADELN LGLASFIFID DNNIECAEVK
AALPEVLVIH LPAIKSKKED SISRLDYLQN IWAFDVNSKS SEDEKRTEFY KQNRLRHALK
SQSTSYKTFL SSLKIKTNIR KATLKDLERI IQLSQRTNQF NLFPNAISDI EFNERVIQQK
SSGCLIIEVS DKYGDYGVVG VVAYDLTNDE LVIRSFFLSC RILGREIEYT VINYLAMIAE
KYNKKGIRLL FKITDKNIPG IGFLQHLANK VELKKVDHIA LLLSDLKKIT PKTIYSSEKN
KKITNHKINT ANDYMLDIAK NCVQSKNRNI DDLNKKYNSI THNKLITVEI SLLELLRKHN
LLVNKKKDTP FVDLGIDSIT CVLIASTIYQ RFNAEIAPFE LLKSDFTFRK LTKYLLNQIK
TNNQEKPEMP MIGVHDARLS FTQQLLWEDE QIFSGTNRNN MFTAYQVEGD INIDIMENTF
VQLMARHDSL RFSFLEHDEE PLLKLNALQS INFKISTFSS DNDEDIKEYV TQFRREPFNL
SRAPLFRVSV IRKKEKETII LFCVHHIIHD GWSLNILIGE FGTIYNAYSK HLPLPDLSTS
SSYINFIQWQ QHHISKELLE KQRAFWNKQL LHIPKLDLIY DKTRKEEYEK PLNHRISFKI
NSKTTHKLKQ ISVINHVTLY DILMSAFGLF LSHYANQNDI NFITAVSGRH HPNVANIVGL
FTSLVLIRMN IDNHESFSDL IKKNKKIIEH IFNNQDLPFN EIIQLTGERV NSKLHAFNQA
GFIFQSYPIN NLIINDKVCK RVFADDKAEL IYDVCDECRF GNLVCFMQEY ESELYGLFEY
NTALFDKKRI KYMIDSFTTL LEHIGEVPNG PARSIPLIST KQYHLLFDKW NQPRVNYSTD
VSLLHYFSEQ VMARENALAV IHNESHLTYG ELDKISNQIA RKLKKEGVAH EIPVGIFLEK
NITRVVAMLS ILKAGGCYVP LEIDTPIYRM NNIMSDAKIL FVLTDSEAGL HFINQYYPEI
KAILVTDNSL QSESNAPLFD TTNPRQLAYI MYTSGSTGNP KGIEIEQGGI LRLVKSSNYI
EINSSDCIAQ TSSFLFDAAT FEIWGALLNG ATLVLIDKNT LLDATSLNAA IKDKKISILF
LTTQLFHAYA HIAPYLFHNL NYVVIGGAAV SYEAVARIFN QKNKPACFIN GYGPTENTTF
STTYSIKNHN DLFNPIPIGK PITGTQVYVL DHALNPRPIG APGKLYVGGV GLARGYINQE
KLNQEKYIYY LNERIYDTGD IVTWKSDGNL KYLGRKDNQI KINGYLVELD EIEVQLETHH
LVVQAIVLVK NEPPHRQLVA YVLLKPGNEL HNVNLYHYLK TILPQYMLPK FYYQIDEVPL
TAQGKVDKNA LLRSDSFAVS YTEYAPPTNI IHEKLICIYA ELLNISPTDI GINTEFFDLG
GTSISALHLI DKVNQQFNIR INFADIYENA NVKSLSEKII ALLSNEICLS GVDYTKFNGN
TLKLVKVGEP QKTPIIFIHP IGGTGFCYLD LIKLLPNDQP CYIIQDPSID ADQILFEDIS
TMAAYYNNLI LNKFKITKFI LAGYSFGGML SLEMVSQLEH QKLDGTIPFV IAFDTWVISD
FLNVEAKEAL RLSIMKQYKR VANELAREHI DPKPWMELHY RRLQNLGFAY NPPMINKKII
LFKANQQLDE FSAMNDLTNY LNAHTSQGVD VYLVSGSHDS ILQYPHVKDI GRLLNQHFKD
NIF
//
