ID G9KRV6_MUSPF Unreviewed; 296 AA.
AC G9KRV6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
DE Flags: Fragment;
GN Name=LOC101682054 {ECO:0000313|RefSeq:XP_004764408.1,
GN ECO:0000313|RefSeq:XP_004764409.1, ECO:0000313|RefSeq:XP_012917844.1,
GN ECO:0000313|RefSeq:XP_044933542.1};
GN Synonyms=SULT1C2 {ECO:0000313|Ensembl:ENSMPUP00000010695.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|EMBL:AES07635.1};
RN [1] {ECO:0000313|EMBL:AES07635.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Lungs {ECO:0000313|EMBL:AES07635.1};
RX PubMed=23236062; DOI=10.1128/JVI.02476-12;
RA Leon A.J., Banner D., Xu L., Ran L., Peng Z., Yi K., Chen C., Xu F.,
RA Huang J., Zhao Z., Lin Z., Huang S.H., Fang Y., Kelvin A.A., Ross T.M.,
RA Farooqui A., Kelvin D.J.;
RT "Sequencing, annotation, and characterization of the influenza ferret
RT infectome.";
RL J. Virol. 87:1957-1966(2013).
RN [2] {ECO:0000313|Ensembl:ENSMPUP00000010695.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_004764408.1, ECO:0000313|RefSeq:XP_004764409.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004764408.1,
RC ECO:0000313|RefSeq:XP_004764409.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3'-phosphoadenylyl sulfate + a phenol = adenosine 3',5'-
CC bisphosphate + an aryl sulfate + H(+); Xref=Rhea:RHEA:12164,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:33853, ChEBI:CHEBI:58339,
CC ChEBI:CHEBI:58343, ChEBI:CHEBI:140317; EC=2.8.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00036572};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Lysosome {ECO:0000256|ARBA:ARBA00004371}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|ARBA:ARBA00005771, ECO:0000256|RuleBase:RU361155}.
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DR EMBL; AEYP01061126; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01061127; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; JP019037; AES07635.1; -; mRNA.
DR RefSeq; XP_004764408.1; XM_004764351.3.
DR RefSeq; XP_004764409.1; XM_004764352.3.
DR RefSeq; XP_012917844.1; XM_013062390.2.
DR RefSeq; XP_044933542.1; XM_045077607.1.
DR STRING; 9669.ENSMPUP00000010695; -.
DR Ensembl; ENSMPUT00000010874.1; ENSMPUP00000010695.1; ENSMPUG00000010783.1.
DR GeneID; 101682054; -.
DR KEGG; mpuf:101682054; -.
DR eggNOG; KOG1584; Eukaryota.
DR GeneTree; ENSGT00940000160912; -.
DR HOGENOM; CLU_027239_1_2_1; -.
DR OMA; PFIEWAQ; -.
DR OrthoDB; 3083090at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR GO; GO:0004062; F:aryl sulfotransferase activity; IEA:Ensembl.
DR GO; GO:0051923; P:sulfation; IEA:Ensembl.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR11783:SF73; SULFOTRANSFERASE 1C2; 1.
DR PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU361155}.
FT DOMAIN 39..288
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AES07635.1"
FT NON_TER 296
FT /evidence="ECO:0000313|EMBL:AES07635.1"
SQ SEQUENCE 296 AA; 34897 MW; CAFF35C734DE3A54 CRC64;
MALAAALEEQ LQLREVSGIP LQASTVDNWS QIQNFEAKPD DLLICTYPKS GTTWIQEIVD
MIEQNGDVEK CQRAIIQHRH PFIEWARPPQ PSGVERANAM PSPRILRTHL PTQLLPPSFW
ENNCKFLYVA RNAKDCMVSY YHFQRMNQIL PDPGTWEEYF ETFISGKVGW GSWFDHVKEW
WEIKDRYQIL FLFYEDIKRD PKYEIQKVMQ FMGKNLDETV LDKIVQETSF EKMKENPMTN
RSTVPKSILD QSISPFMRKG TVGDWKNHFT VAQNERFDEI YRQKMKGTSI KFLTEL
//
