ID G9MGJ7_HYPVG Unreviewed; 1155 AA.
AC G9MGJ7;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Prion-inhibition and propagation HeLo domain-containing protein {ECO:0000259|Pfam:PF14479};
GN ORFNames=TRIVIDRAFT_188908 {ECO:0000313|EMBL:EHK26644.1};
OS Hypocrea virens (strain Gv29-8 / FGSC 10586) (Gliocladium virens)
OS (Trichoderma virens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=413071 {ECO:0000313|EMBL:EHK26644.1, ECO:0000313|Proteomes:UP000007115};
RN [1] {ECO:0000313|EMBL:EHK26644.1, ECO:0000313|Proteomes:UP000007115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Gv29-8 / FGSC 10586 {ECO:0000313|Proteomes:UP000007115};
RX PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40;
RA Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A.,
RA Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A.,
RA Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., Antal Z.,
RA Atanasova L., Cervantes-Badillo M.G., Challacombe J., Chertkov O.,
RA McCluskey K., Coulpier F., Deshpande N., von Doehren H., Ebbole D.J.,
RA Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F.,
RA Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R.,
RA Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E.,
RA Lucas S., Luebeck M., Luebeck P.S., Margeot A., Metz B., Misra M.,
RA Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E.,
RA Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S.,
RA Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M.,
RA Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.;
RT "Comparative genome sequence analysis underscores mycoparasitism as the
RT ancestral life style of Trichoderma.";
RL Genome Biol. 12:R40.1-R40.15(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK26644.1}.
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DR EMBL; ABDF02000002; EHK26644.1; -; Genomic_DNA.
DR RefSeq; XP_013960842.1; XM_014105367.1.
DR AlphaFoldDB; G9MGJ7; -.
DR STRING; 413071.G9MGJ7; -.
DR EnsemblFungi; EHK26644; EHK26644; TRIVIDRAFT_188908.
DR GeneID; 25789375; -.
DR VEuPathDB; FungiDB:TRIVIDRAFT_188908; -.
DR eggNOG; KOG0553; Eukaryota.
DR HOGENOM; CLU_011377_0_0_1; -.
DR InParanoid; G9MGJ7; -.
DR OMA; WPYINEV; -.
DR OrthoDB; 1748714at2759; -.
DR Proteomes; UP000007115; Unassembled WGS sequence.
DR Gene3D; 1.20.120.1020; Prion-inhibition and propagation, HeLo domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR029498; HeLo_dom.
DR InterPro; IPR038305; HeLo_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR42345:SF2; -; 1.
DR PANTHER; PTHR42345; TPR_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14479; HeLo; 1.
DR Pfam; PF07719; TPR_2; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 2.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007115};
KW Signal {ECO:0000256|SAM:SignalP};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1155
FT /note="Prion-inhibition and propagation HeLo domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003523601"
FT DOMAIN 7..238
FT /note="Prion-inhibition and propagation HeLo"
FT /evidence="ECO:0000259|Pfam:PF14479"
FT REPEAT 628..661
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 696..729
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 129..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..296
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1155 AA; 130558 MW; 97932E7F27F771C9 CRC64;
MTDIAGLVFG VAALWQSCVQ AYEIIDSTRH HGMEFELLNV KFEVERVRLL CWGDALGLAG
VQTWAWNPGT SPNSGDQSNI NTTRLDVRLR QEDVRSTVLR LLGCIQHVFE NTDRLQDYYG
LQEAAPLGLT SQGQSQTQSH GQEQEPLPPQ TQRILIGVFK RPYENLRRMA GHRQRSTALN
RRVVWAVRDR RKFDMLISEL RGFNDSLESL FPDAQIRAAA AMRAEIEGAV EIRGLRLLQE
ATAEEHQDLS ECASLRLELL SVSRIQDDVT SQATTENTWA KDGWEDADEE IPRGNQQAEA
EGRTTPTEAT QEEPELDEMT KRLRELDLYN AKKSFGAVTL SLIGPHGGLA HVSGHVYWIG
DKTDRTFPSP WQDRDKGFVS TTHAAFEIYK RKKYMKKPSR DKYWSHDSED YALLDPESHV
KFENENPGTV TVEGYGLECW DFETTKPRNR EQLITVNYSD LPVLPARTLL RRIDDLQNHA
GKFGWSPDKE ELDLKEVVGT LGIVYYDAKY AKDPSRWIGD LYSLLNRTDV FADFTTSSTI
GEQWAGTTDD GCIGTWNLLR QIIVGRELAL RLKHLDEGTS WSGFTERVLA SLIVSDLWLK
HVQIVLTDAK LPADSPEGPE TAEQKAQAED YKNQGNEALK KNEYQKAVDL YTEAIKIDLS
NAIYRCNRSA ALIGLDMFLE AEEDAYVATL LDPKYAKAWS RLGMAIFKQG DAKRAKKAYE
RALQVAGKDT TAQMRQGLAS AEEMIKEKIK AINSEKDIAK QHKLRSAFLD EDWEIFGKAP
EFHSLVHEQQ VEGLLLFAER MRWPYINEVR DYAEDVYSSL HTGGTVGIHL HDWLYGLVLP
GKWFAFKIMT ALILCTPSIR DKTGIAPYFD CGLVLPTRSY WRLRTVLGRV LGCLPGIISL
CGWIGPCPKV EFDPPVERPV QPHHVRVKAR RIALTEHSTN QDDGVWGRSL YDRRRATDIR
PDEEMEPYMA EMRNPSNWVI PEPPVRDVGT CKILSIQLKK LAPQVGAARK AAEGKIQDSQ
AEHEAEYRAS ITFKMDNNEE AVTYKLFTNP VFVTPPPCNE GPRGAHEVHM RGLQLFQKNI
WSLDRLKDHT AEDTDDDEVM VINATGNGAE VLARAWCSER GKCAVIRRPG GPCFVCAVRA
ASRESLGTRV LIWTG
//
