ID G9MH88_HYPVG Unreviewed; 741 AA.
AC G9MH88;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Amino acid transporter transmembrane domain-containing protein {ECO:0000259|Pfam:PF01490};
GN ORFNames=TRIVIDRAFT_211573 {ECO:0000313|EMBL:EHK26076.1};
OS Hypocrea virens (strain Gv29-8 / FGSC 10586) (Gliocladium virens)
OS (Trichoderma virens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=413071 {ECO:0000313|EMBL:EHK26076.1, ECO:0000313|Proteomes:UP000007115};
RN [1] {ECO:0000313|EMBL:EHK26076.1, ECO:0000313|Proteomes:UP000007115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Gv29-8 / FGSC 10586 {ECO:0000313|Proteomes:UP000007115};
RX PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40;
RA Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A.,
RA Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A.,
RA Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., Antal Z.,
RA Atanasova L., Cervantes-Badillo M.G., Challacombe J., Chertkov O.,
RA McCluskey K., Coulpier F., Deshpande N., von Doehren H., Ebbole D.J.,
RA Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F.,
RA Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R.,
RA Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E.,
RA Lucas S., Luebeck M., Luebeck P.S., Margeot A., Metz B., Misra M.,
RA Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E.,
RA Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S.,
RA Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M.,
RA Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.;
RT "Comparative genome sequence analysis underscores mycoparasitism as the
RT ancestral life style of Trichoderma.";
RL Genome Biol. 12:R40.1-R40.15(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC {ECO:0000256|ARBA:ARBA00008066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK26076.1}.
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DR EMBL; ABDF02000002; EHK26076.1; -; Genomic_DNA.
DR RefSeq; XP_013960291.1; XM_014104816.1.
DR AlphaFoldDB; G9MH88; -.
DR STRING; 413071.G9MH88; -.
DR EnsemblFungi; EHK26076; EHK26076; TRIVIDRAFT_211573.
DR GeneID; 25790625; -.
DR VEuPathDB; FungiDB:TRIVIDRAFT_211573; -.
DR eggNOG; KOG1304; Eukaryota.
DR HOGENOM; CLU_009646_3_1_1; -.
DR InParanoid; G9MH88; -.
DR OMA; QESMKQP; -.
DR OrthoDB; 3601817at2759; -.
DR Proteomes; UP000007115; Unassembled WGS sequence.
DR GO; GO:0000329; C:fungal-type vacuole membrane; IEA:EnsemblFungi.
DR GO; GO:0061459; F:L-arginine transmembrane transporter activity; IEA:EnsemblFungi.
DR GO; GO:0005290; F:L-histidine transmembrane transporter activity; IEA:EnsemblFungi.
DR GO; GO:0015189; F:L-lysine transmembrane transporter activity; IEA:EnsemblFungi.
DR GO; GO:1990818; P:L-arginine transmembrane export from vacuole; IEA:EnsemblFungi.
DR GO; GO:0089708; P:L-histidine transmembrane export from vacuole; IEA:EnsemblFungi.
DR GO; GO:0089707; P:L-lysine transmembrane export from vacuole; IEA:EnsemblFungi.
DR InterPro; IPR013057; AA_transpt_TM.
DR PANTHER; PTHR22950; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR22950:SF666; VACUOLAR AMINO ACID TRANSPORTER 3; 1.
DR Pfam; PF01490; Aa_trans; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007115};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 372..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 481..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 556..579
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 599..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 645..662
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 668..684
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 704..725
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 341..721
FT /note="Amino acid transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01490"
FT REGION 29..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 203..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..225
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..319
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 741 AA; 81422 MW; D4B4BB57C0C79AEC CRC64;
MPHLPFLSQI CQVRPFSSSL PRDEVTARLA EPVRSSSPMM RSGSPRPGFS KPEGGALGEG
SAFAQGPGVS ALAAALSDSL GQTPPRHGTP PARVRTPPVR PQSPSGIGRS ATPTNYGSFD
SRGRPGAEST GPFEDPEIVK RHLVHPSEMD KPTSEASSET GKGKQTADFG FGTTGLHEDE
FSSLRLQGGD VTRGIYKWTE QAEAKTRMQR SKSFDHSRPE PESETLDINS IKVPGGFRRN
HLRRNVISPS GDHENGYGGA DSPGSNRPLF TSSFLEFLTI YGHFAGEELE EDDEVLGPNE
YFQSGEDNGE EEDEEPMEDS ALLGPSKKKR KRKVRGGSGQ NSQMNAALLL LKSFVGTGVL
FLPRAYLNGG MLFSNLVLLG VALLSYYCFV LLVTTRLHVE GSFGDMGGIL YGKWMRAVIL
ASIVLSQVGF VAAYIVFTSE NLQAFILAVT NCRTSISIPM LILMQMVVFL PFSLLRDIGK
LGFTALIADA FILIGLAYLF YYDVLTLAAE GLADIIMFNQ RDWTLFIGTA IFTFEGIGLI
IPIQESMKQP EKFPKVMFLV MIIITVLFTV MGAISYAAYG SKTQTVVLLN LPQDNRMVNV
VQLLYSVAIL LSTPLQIFPA IRIAETELFT RSGKYNPWIK WQKNIFRFFV VMLCAAIAWG
GADNLDKFVA LVGNFACIPL VYIYPPLLHY KAVARNRFWR WSDIGLCIFG FIAMAYTTSL
TVMSWANSEP KAPGYCDRRG P
//
