ID G9MYQ1_HYPVG Unreviewed; 961 AA.
AC G9MYQ1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=DNA mismatch repair protein S5 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TRIVIDRAFT_48473 {ECO:0000313|EMBL:EHK20231.1};
OS Hypocrea virens (strain Gv29-8 / FGSC 10586) (Gliocladium virens)
OS (Trichoderma virens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=413071 {ECO:0000313|EMBL:EHK20231.1, ECO:0000313|Proteomes:UP000007115};
RN [1] {ECO:0000313|EMBL:EHK20231.1, ECO:0000313|Proteomes:UP000007115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Gv29-8 / FGSC 10586 {ECO:0000313|Proteomes:UP000007115};
RX PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40;
RA Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A.,
RA Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A.,
RA Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., Antal Z.,
RA Atanasova L., Cervantes-Badillo M.G., Challacombe J., Chertkov O.,
RA McCluskey K., Coulpier F., Deshpande N., von Doehren H., Ebbole D.J.,
RA Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F.,
RA Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R.,
RA Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E.,
RA Lucas S., Luebeck M., Luebeck P.S., Margeot A., Metz B., Misra M.,
RA Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E.,
RA Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S.,
RA Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M.,
RA Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.;
RT "Comparative genome sequence analysis underscores mycoparasitism as the
RT ancestral life style of Trichoderma.";
RL Genome Biol. 12:R40.1-R40.15(2011).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK20231.1}.
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DR EMBL; ABDF02000080; EHK20231.1; -; Genomic_DNA.
DR RefSeq; XP_013954429.1; XM_014098954.1.
DR AlphaFoldDB; G9MYQ1; -.
DR STRING; 413071.G9MYQ1; -.
DR EnsemblFungi; EHK20231; EHK20231; TRIVIDRAFT_48473.
DR GeneID; 25794783; -.
DR VEuPathDB; FungiDB:TRIVIDRAFT_48473; -.
DR eggNOG; KOG1978; Eukaryota.
DR HOGENOM; CLU_004131_0_0_1; -.
DR InParanoid; G9MYQ1; -.
DR OMA; RMRIIGQ; -.
DR OrthoDB; 4698638at2759; -.
DR Proteomes; UP000007115; Unassembled WGS sequence.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0061982; P:meiosis I cell cycle process; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd16926; HATPase_MutL-MLH-PMS-like; 1.
DR CDD; cd03484; MutL_Trans_hPMS_2_like; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.1540.20; MutL, C-terminal domain, dimerisation subdomain; 1.
DR Gene3D; 3.30.1370.100; MutL, C-terminal domain, regulatory subdomain; 1.
DR InterPro; IPR014762; DNA_mismatch_repair_CS.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR014790; MutL_C.
DR InterPro; IPR042120; MutL_C_dimsub.
DR InterPro; IPR042121; MutL_C_regsub.
DR InterPro; IPR037198; MutL_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF52; MISMATCH REPAIR ENDONUCLEASE PMS2; 1.
DR Pfam; PF01119; DNA_mis_repair; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF08676; MutL_C; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SMART; SM00853; MutL_C; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF118116; DNA mismatch repair protein MutL; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Reference proteome {ECO:0000313|Proteomes:UP000007115}.
FT DOMAIN 217..357
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT DOMAIN 738..899
FT /note="MutL C-terminal dimerisation"
FT /evidence="ECO:0000259|SMART:SM00853"
FT REGION 402..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 692..716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..576
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 591..608
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..629
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..658
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 697..713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 961 AA; 106566 MW; 65A8FD66B1DB9907 CRC64;
MATIKQIDGR SVHQIQSGQV IVDLCSVVKE LVENSVDSGA TIIDVRFKNQ GLDSIEVQDN
GSGISPANYS SVALKHYTSK LSSYSDIESL QTFGFRGEAL ASLCALSILT VTTCLEQESP
KGSRLTFHQS GELDSTTVVA AQRGTTVTVE NLFHNLPVRR RELDRNIKRE WHKVIALLNQ
YACIQTNVKF SVSQQPTKGK RILLFSTKGN PTTRDNIINI FGAKTLTALI PLDLHLELKP
SGTRSDVRIG DKLGPNSHDV RIVGHISKPA HGEGRQTPDR QMFFVNGRPC SLPQLAKAFN
EVYRSYNNSQ SPFIFADVQL DTMLYDVNVS PDKRSILLHD QNNLLDTLRS SLSQLFDTHE
DSISIATSTQ NVKAQSSYSK FTKPGQLPRL LGESAYKSYT TTAVEHSPSY EDNKSSSTTD
TEEPEPDDEI PQASRSMKTR PQCNTKEKLH LHNGIESVVR RDISSSPEKP APEPTHLKTV
LVDHSPRPKA SSATSNINTV INQPQRSHGP NFKIHPEISD STSPVASDIS VEDQGSQELH
AVVTPLREVT SLAKATDVEG KARSLEPEKL HSTLPEPGEA KELLPSEISR LDTESIIQQP
SPTRRNRRAM DNNISRQSRD DKQSLETEPD SQHLKSTLVT TDGGSPMNTA NAGALSVESR
IQPSKPARRK DITTGYIQSL HVEKGKLRLL HNKRPRLRTS QPGSTSHNAS SVERIDASDA
ESRLPLIISK GDFSKMRIIG QFNLGFIIAV KPASRLGSGV EGKYDELFII DQHASDEKYN
YEKLQNTTEI QSQRLVHPKR LQLTALEEEI ILENATALNA NGFKVNIDTT GRFSVGSRCQ
LTSLPLSREV TFKLDDLEEL ISLLGDKSAE SSYIPRPSKV QKMFAMRACR SSIMIGKAMT
KSQMHSLVNH MGELDKPWNC PHGRPTIRHL SRLQAWSGVG WERDLQTDSI TAWHDYMGEA
N
//
