ID G9N3N8_HYPVG Unreviewed; 503 AA.
AC G9N3N8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Amino acid transporter transmembrane domain-containing protein {ECO:0000259|Pfam:PF01490};
GN ORFNames=TRIVIDRAFT_80721 {ECO:0000313|EMBL:EHK18921.1};
OS Hypocrea virens (strain Gv29-8 / FGSC 10586) (Gliocladium virens)
OS (Trichoderma virens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=413071 {ECO:0000313|EMBL:EHK18921.1, ECO:0000313|Proteomes:UP000007115};
RN [1] {ECO:0000313|EMBL:EHK18921.1, ECO:0000313|Proteomes:UP000007115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Gv29-8 / FGSC 10586 {ECO:0000313|Proteomes:UP000007115};
RX PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40;
RA Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A.,
RA Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A.,
RA Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., Antal Z.,
RA Atanasova L., Cervantes-Badillo M.G., Challacombe J., Chertkov O.,
RA McCluskey K., Coulpier F., Deshpande N., von Doehren H., Ebbole D.J.,
RA Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F.,
RA Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R.,
RA Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E.,
RA Lucas S., Luebeck M., Luebeck P.S., Margeot A., Metz B., Misra M.,
RA Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E.,
RA Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S.,
RA Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M.,
RA Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.;
RT "Comparative genome sequence analysis underscores mycoparasitism as the
RT ancestral life style of Trichoderma.";
RL Genome Biol. 12:R40.1-R40.15(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC {ECO:0000256|ARBA:ARBA00008066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK18921.1}.
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DR EMBL; ABDF02000085; EHK18921.1; -; Genomic_DNA.
DR RefSeq; XP_013953118.1; XM_014097643.1.
DR AlphaFoldDB; G9N3N8; -.
DR STRING; 413071.G9N3N8; -.
DR EnsemblFungi; EHK18921; EHK18921; TRIVIDRAFT_80721.
DR GeneID; 25798195; -.
DR VEuPathDB; FungiDB:TRIVIDRAFT_80721; -.
DR eggNOG; KOG1305; Eukaryota.
DR HOGENOM; CLU_009020_1_0_1; -.
DR InParanoid; G9N3N8; -.
DR OMA; DSIHHQR; -.
DR OrthoDB; 5485318at2759; -.
DR Proteomes; UP000007115; Unassembled WGS sequence.
DR GO; GO:0000329; C:fungal-type vacuole membrane; IEA:EnsemblFungi.
DR GO; GO:0061459; F:L-arginine transmembrane transporter activity; IEA:EnsemblFungi.
DR GO; GO:0005313; F:L-glutamate transmembrane transporter activity; IEA:EnsemblFungi.
DR GO; GO:0005290; F:L-histidine transmembrane transporter activity; IEA:EnsemblFungi.
DR GO; GO:0015189; F:L-lysine transmembrane transporter activity; IEA:EnsemblFungi.
DR GO; GO:0015194; F:L-serine transmembrane transporter activity; IEA:EnsemblFungi.
DR GO; GO:0005302; F:L-tyrosine transmembrane transporter activity; IEA:EnsemblFungi.
DR GO; GO:0090518; P:L-arginine transmembrane import into vacuole; IEA:EnsemblFungi.
DR GO; GO:1901481; P:L-glutamate import involved in cellular response to nitrogen starvation; IEA:EnsemblFungi.
DR GO; GO:0090515; P:L-glutamate transmembrane import into vacuole; IEA:EnsemblFungi.
DR GO; GO:0090513; P:L-histidine transmembrane import into vacuole; IEA:EnsemblFungi.
DR GO; GO:1901482; P:L-lysine import into vacuole involved in cellular response to nitrogen starvation; IEA:EnsemblFungi.
DR GO; GO:0090516; P:L-serine transmembrane import into vacuole; IEA:EnsemblFungi.
DR GO; GO:0090514; P:L-tyrosine transmembrane import into vacuole; IEA:EnsemblFungi.
DR InterPro; IPR013057; AA_transpt_TM.
DR PANTHER; PTHR22950; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR22950:SF646; SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 10-RELATED; 1.
DR Pfam; PF01490; Aa_trans; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007115};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 480..502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..414
FT /note="Amino acid transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01490"
FT REGION 320..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 503 AA; 54011 MW; F43FB4CA5E8ADCA7 CRC64;
MARSRRRAGK DGHGGQASMG SSVVNLLNTI VGAGTLAMPS VLSHMGIMLG TLLIIWSGFT
SAFGLYLQSR CARYLDRGTS SFFALSQLTY PNASVIFDAA IAIKCFGVGV SYMIIIGDLM
PGVALGFNSN ADKIPYLVDR NFWITAFMLL VIPLSFLKRL DSLKYTSIVA LVSIGYLIIL
VIYHFSVDPH ADPSNIRVIQ WAGAVETLSA LPVVVFAYTC HQNMFSIINE IKDNSPPSIV
RVVGSSIGSA ASIYVLVAIT GYITFGNSIV GNIVSMYPTG VASTIGKAAI VVLVLFSIPL
QVHPCRASLD AVFNWRPSRG NSSGGRAGSP LLNSSSAQRG DHGSTAPMSD LRFALITTII
LTLAYITALS VSSLDRVLAF VGSTGSTSIS FILPGLFYYK ISDPESVHHQ RLAKEDDDMD
GSDDSDVEDS GALAQSTHSI RSAASAASNR SGSALRWRRK WRWDLEHVDN GLLRKMALAL
AIYGMVVMVV CLVMNIFFIT AAH
//
