ID G9N4N0_HYPVG Unreviewed; 507 AA.
AC G9N4N0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Histone chaperone RTT106/FACT complex subunit SPT16-like middle domain-containing protein {ECO:0000259|SMART:SM01287};
GN ORFNames=TRIVIDRAFT_59389 {ECO:0000313|EMBL:EHK18554.1};
OS Hypocrea virens (strain Gv29-8 / FGSC 10586) (Gliocladium virens)
OS (Trichoderma virens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=413071 {ECO:0000313|EMBL:EHK18554.1, ECO:0000313|Proteomes:UP000007115};
RN [1] {ECO:0000313|EMBL:EHK18554.1, ECO:0000313|Proteomes:UP000007115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Gv29-8 / FGSC 10586 {ECO:0000313|Proteomes:UP000007115};
RX PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40;
RA Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A.,
RA Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A.,
RA Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., Antal Z.,
RA Atanasova L., Cervantes-Badillo M.G., Challacombe J., Chertkov O.,
RA McCluskey K., Coulpier F., Deshpande N., von Doehren H., Ebbole D.J.,
RA Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F.,
RA Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R.,
RA Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E.,
RA Lucas S., Luebeck M., Luebeck P.S., Margeot A., Metz B., Misra M.,
RA Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E.,
RA Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S.,
RA Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M.,
RA Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.;
RT "Comparative genome sequence analysis underscores mycoparasitism as the
RT ancestral life style of Trichoderma.";
RL Genome Biol. 12:R40.1-R40.15(2011).
CC -!- FUNCTION: Histones H3 and H4 chaperone involved in the nucleosome
CC formation and heterochromatin silencing. Required for the deposition of
CC H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role
CC in the transcriptional regulation of the cell-cycle dependent histone
CC genes by creating a repressive structure at the core histone gene
CC promoter. {ECO:0000256|ARBA:ARBA00037550}.
CC -!- SUBUNIT: Interacts with histones H3 and H4.
CC {ECO:0000256|ARBA:ARBA00038654}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC -!- SIMILARITY: Belongs to the RTT106 family.
CC {ECO:0000256|ARBA:ARBA00006159}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK18554.1}.
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DR EMBL; ABDF02000086; EHK18554.1; -; Genomic_DNA.
DR RefSeq; XP_013952750.1; XM_014097275.1.
DR AlphaFoldDB; G9N4N0; -.
DR STRING; 413071.G9N4N0; -.
DR EnsemblFungi; EHK18554; EHK18554; TRIVIDRAFT_59389.
DR GeneID; 25795943; -.
DR VEuPathDB; FungiDB:TRIVIDRAFT_59389; -.
DR eggNOG; ENOG502R9PE; Eukaryota.
DR HOGENOM; CLU_033828_0_0_1; -.
DR InParanoid; G9N4N0; -.
DR OMA; AMPEAHR; -.
DR OrthoDB; 1359279at2759; -.
DR Proteomes; UP000007115; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR Gene3D; 2.30.29.120; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR013719; RTT106/SPT16-like_middle_dom.
DR PANTHER; PTHR45849; FACT COMPLEX SUBUNIT SSRP1; 1.
DR PANTHER; PTHR45849:SF3; HISTONE CHAPERONE RTT106; 1.
DR Pfam; PF08512; Rttp106-like_middle; 1.
DR SMART; SM01287; Rtt106; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007115}.
FT DOMAIN 243..337
FT /note="Histone chaperone RTT106/FACT complex subunit SPT16-
FT like middle"
FT /evidence="ECO:0000259|SMART:SM01287"
FT REGION 51..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 337..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 488..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 337..363
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..387
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..457
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..507
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 507 AA; 55415 MW; B3AA8F2CF5F0F755 CRC64;
MAQSLNSQRI DAIFQSRPDI IARINQAADS AGRIALFNDI ADHVYERLQE NGEPAQKRRK
VGAEQANGSP SSQVVLSNAA DEAVLLEIKE ISVSVPQRKK LEICFTSNHL YARAPGTTAP
LQGISYAWRD IEYAFYLPVP DKAQVQYNYI IFPKGTCLPA KTGAPPSAEP FVFTVPVTAP
KQGTIGGSEA GAAAAVSDTY KSLFHWALTK RLQAAGSTVK IVSADPNKFR SMVRQPHRPN
ETAVHVSGFR GSKDGYLFLL ENGILWGFKK PLIFIPTNRI AAISYTNILQ ITFNMVVEIF
TEEDGKTEEL EFGMLDQQNY GGIDDYIKMN GLQDRSMAEQ RKAKLQLAEN KGPKKKDGDA
ANGDAEAAEG EGDGMTELER AQLEAEQQLQ DDEDEDEEDY DPGSEGDSEG SGSSDDDDDD
DDDDDDDEDD GEDDGEEEEG GEEEEEAEGE QEEEEEVKEE PPKPAAPPAK TETPSVPVRT
GWAAFTSRPA ADVDMAEGDD EKFDVVG
//
