ID G9N708_HYPVG Unreviewed; 217 AA.
AC G9N708;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 03-MAY-2023, entry version 53.
DE RecName: Full=DNA replication complex GINS protein PSF1 {ECO:0000256|ARBA:ARBA00015143, ECO:0000256|RuleBase:RU368085};
GN ORFNames=TRIVIDRAFT_57368 {ECO:0000313|EMBL:EHK17506.1};
OS Hypocrea virens (strain Gv29-8 / FGSC 10586) (Gliocladium virens)
OS (Trichoderma virens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=413071 {ECO:0000313|EMBL:EHK17506.1, ECO:0000313|Proteomes:UP000007115};
RN [1] {ECO:0000313|EMBL:EHK17506.1, ECO:0000313|Proteomes:UP000007115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Gv29-8 / FGSC 10586 {ECO:0000313|Proteomes:UP000007115};
RX PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40;
RA Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A.,
RA Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A.,
RA Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., Antal Z.,
RA Atanasova L., Cervantes-Badillo M.G., Challacombe J., Chertkov O.,
RA McCluskey K., Coulpier F., Deshpande N., von Doehren H., Ebbole D.J.,
RA Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F.,
RA Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R.,
RA Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E.,
RA Lucas S., Luebeck M., Luebeck P.S., Margeot A., Metz B., Misra M.,
RA Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E.,
RA Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S.,
RA Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M.,
RA Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.;
RT "Comparative genome sequence analysis underscores mycoparasitism as the
RT ancestral life style of Trichoderma.";
RL Genome Biol. 12:R40.1-R40.15(2011).
CC -!- FUNCTION: Required for correct functioning of the GINS complex, a
CC complex that plays an essential role in the initiation of DNA
CC replication, and progression of DNA replication forks. GINS complex
CC seems to bind preferentially to single-stranded DNA.
CC {ECO:0000256|RuleBase:RU368085}.
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. {ECO:0000256|ARBA:ARBA00002340}.
CC -!- SUBUNIT: Component of the GINS complex.
CC {ECO:0000256|RuleBase:RU368085}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU368085}.
CC -!- SIMILARITY: Belongs to the GINS1/PSF1 family.
CC {ECO:0000256|ARBA:ARBA00006677, ECO:0000256|RuleBase:RU368085}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK17506.1}.
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DR EMBL; ABDF02000088; EHK17506.1; -; Genomic_DNA.
DR RefSeq; XP_013951708.1; XM_014096233.1.
DR AlphaFoldDB; G9N708; -.
DR STRING; 413071.G9N708; -.
DR EnsemblFungi; EHK17506; EHK17506; TRIVIDRAFT_57368.
DR GeneID; 25795714; -.
DR VEuPathDB; FungiDB:TRIVIDRAFT_57368; -.
DR eggNOG; KOG3303; Eukaryota.
DR HOGENOM; CLU_079191_0_0_1; -.
DR InParanoid; G9N708; -.
DR OMA; NHLCMRR; -.
DR OrthoDB; 166901at2759; -.
DR Proteomes; UP000007115; Unassembled WGS sequence.
DR GO; GO:0071162; C:CMG complex; IEA:EnsemblFungi.
DR GO; GO:0000811; C:GINS complex; IEA:UniProtKB-UniRule.
DR GO; GO:0031298; C:replication fork protection complex; IEA:EnsemblFungi.
DR GO; GO:1902983; P:DNA strand elongation involved in mitotic DNA replication; IEA:EnsemblFungi.
DR GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:EnsemblFungi.
DR GO; GO:0000727; P:double-strand break repair via break-induced replication; IEA:EnsemblFungi.
DR GO; GO:1902975; P:mitotic DNA replication initiation; IEA:EnsemblFungi.
DR CDD; cd11710; GINS_A_psf1; 1.
DR CDD; cd21696; GINS_B_Psf1; 1.
DR Gene3D; 1.20.58.1030; -; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR005339; GINS_Psf1.
DR PANTHER; PTHR12914:SF2; DNA REPLICATION COMPLEX GINS PROTEIN PSF1; 1.
DR PANTHER; PTHR12914; PARTNER OF SLD5; 1.
DR Pfam; PF05916; Sld5; 1.
DR SUPFAM; SSF158573; GINS helical bundle-like; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU368085};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU368085};
KW Reference proteome {ECO:0000313|Proteomes:UP000007115}.
FT DOMAIN 21..136
FT /note="GINS subunit"
FT /evidence="ECO:0000259|Pfam:PF05916"
FT REGION 111..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 217 AA; 24260 MW; E5337DC98592F1EC CRC64;
MYGDLGIKLV QHAKRTQNLA HLPPYQTELV RAVTREVRDL NKDVDDLLEP FQGSFDPAED
QAVAYTLLVN HISMRRNKRC LLAYHRTRTD KLEELVWNGA DVIDLSGQQV RDAGASGSGK
GVTSGDGSTS SLSPQEEDYV RQYGDLLAAY KGQWTDIDLT GSLEPPRDLF IDVRVLKDAG
EIQTEYGAIT LTKNSQFYVR QGDVERLIAQ GYLQKLS
//
