ID G9NA35_HYPVG Unreviewed; 1150 AA.
AC G9NA35;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=DUF726-domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=TRIVIDRAFT_132407 {ECO:0000313|EMBL:EHK16802.1};
OS Hypocrea virens (strain Gv29-8 / FGSC 10586) (Gliocladium virens)
OS (Trichoderma virens).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=413071 {ECO:0000313|EMBL:EHK16802.1, ECO:0000313|Proteomes:UP000007115};
RN [1] {ECO:0000313|EMBL:EHK16802.1, ECO:0000313|Proteomes:UP000007115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Gv29-8 / FGSC 10586 {ECO:0000313|Proteomes:UP000007115};
RX PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40;
RA Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A.,
RA Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A.,
RA Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., Antal Z.,
RA Atanasova L., Cervantes-Badillo M.G., Challacombe J., Chertkov O.,
RA McCluskey K., Coulpier F., Deshpande N., von Doehren H., Ebbole D.J.,
RA Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F.,
RA Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R.,
RA Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E.,
RA Lucas S., Luebeck M., Luebeck P.S., Margeot A., Metz B., Misra M.,
RA Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E.,
RA Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S.,
RA Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M.,
RA Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.;
RT "Comparative genome sequence analysis underscores mycoparasitism as the
RT ancestral life style of Trichoderma.";
RL Genome Biol. 12:R40.1-R40.15(2011).
CC -!- SIMILARITY: Belongs to the TMCO4 family.
CC {ECO:0000256|ARBA:ARBA00009824}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK16802.1}.
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DR EMBL; ABDF02000090; EHK16802.1; -; Genomic_DNA.
DR RefSeq; XP_013950998.1; XM_014095523.1.
DR AlphaFoldDB; G9NA35; -.
DR EnsemblFungi; EHK16802; EHK16802; TRIVIDRAFT_132407.
DR GeneID; 25787560; -.
DR VEuPathDB; FungiDB:TRIVIDRAFT_132407; -.
DR eggNOG; KOG2385; Eukaryota.
DR HOGENOM; CLU_001695_1_0_1; -.
DR InParanoid; G9NA35; -.
DR OMA; KEVGWEV; -.
DR OrthoDB; 8526at2759; -.
DR Proteomes; UP000007115; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035650; F:AP-1 adaptor complex binding; IEA:EnsemblFungi.
DR GO; GO:0035652; P:clathrin-coated vesicle cargo loading; IEA:EnsemblFungi.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007941; DUF726.
DR PANTHER; PTHR17920:SF24; LIPASE MIL1-RELATED; 1.
DR PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR Pfam; PF05277; DUF726; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007115};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 533..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 577..598
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 922..945
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 962..1150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 878..905
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 37..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1029..1046
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1065..1127
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHK16802.1"
FT NON_TER 1150
FT /evidence="ECO:0000313|EMBL:EHK16802.1"
SQ SEQUENCE 1150 AA; 126435 MW; 9FDC6CEEB27B11E1 CRC64;
VEVDDFGLPL KRFIAPAAEP PDSDAQDATN DANTSNETQD GRHESKEERQ KTTEAAGSKN
GRTSGSDSED TGPKGVQPTR ENISTAASPI QQQESKTETE TSRNEPLSPP ANNSPWSPTS
PSSTKGTRAI EAPSTPKTPK TPNRGVQPSE KFLQPKTPEQ FSQTQRRDRS FSSPASNNGV
SEYSHQHVLQ RQEEKEEKKE DDDGGWQEMP SYARYDMYDD DDRLIAREHD ADEDETYGYA
GLGGAGKGYT RVIMDEDAES ATSMDEHTQY LFKNPNGTSI GEDDEARDAV SQMQATKDLL
TEGQRIAYVG VVRLEIVNMV KEAEKLQVTA KSAKKQVVMG AEAVKMWGQK MMIRVYAHMD
ISDAEQIMIE QLADHGVMAQ DLTPALLANS RVQNPMAEEK KLGTPRSSRY PPPYEEEKPA
EMPPPYETHS GEELPEVKTP SQMPTTEKID IDLRWTVLCD LFLILIADSV YDARSRTLLE
RVGKSLDITW IDICKFEKKV TDALEMQQAA EKENWNEEEH MENRRKMALK KRYIMMGLAT
VGGGLVIGLS AGLLAPVIGA GLAAGFTTIG VTGTSSFLAG AGGAAIITSS AAASGGIIGG
KAAGRRTGAV KTFEYRPLHN NKRVNLIVTV SGWLTGKVDD VRLPFSTVDP IMGDIYSVLW
EPEMLRSMGD TINILATEQV LGSTILVSLM AAIQLPVVLT KLSYLIDNPW AVSLDRATSA
GLILADSLIE RSLGTRPITL VGYSLGARVI FSCLKELAKK GAFGLVQNVY MFGSPIVANR
DDFLKARSVV SGRFVNGYNR NDWILGYLFR LTNGGIRRVA GLGSLDDCPW IESVDVTDLV
AGHMEYRKAM PSLLTRCGWI VTSEEFSEIE DPDPDDHQGR QRELINEIEE ARRELEREGR
AGKRTSKFGL FGRRNKAERQ EWEIYEDSGK DSPKPGKKVE DKDGNNYGVL FDIDAIRAEL
AKEAENDGNE EIQVKEIKST LPPMKLDYSP VSSPQTPARG ANLEPHRDSW QTSKSAEVLP
MRFSNGGYSP RDQPATTAGT PTTRPSPSPY LYEPSHHEDE IQMTFDTSFQ ESPRRHSTFD
GGSSAFDRGS STFGGGSSAF DKGSSTFDGG SSRPEIKTSS TVPNVTLADP WNDPDDDDFG
KEQEISMTFA
//
