ID G9NNS7_HYPAI Unreviewed; 971 AA.
AC G9NNS7;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=ER membrane protein complex subunit 1 {ECO:0000256|ARBA:ARBA00020824};
GN ORFNames=TRIATDRAFT_154130 {ECO:0000313|EMBL:EHK47718.1};
OS Hypocrea atroviridis (strain ATCC 20476 / IMI 206040) (Trichoderma
OS atroviride).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=452589 {ECO:0000313|EMBL:EHK47718.1, ECO:0000313|Proteomes:UP000005426};
RN [1] {ECO:0000313|EMBL:EHK47718.1, ECO:0000313|Proteomes:UP000005426}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20476 / IMI 206040 {ECO:0000313|Proteomes:UP000005426};
RX PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40;
RA Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A.,
RA Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A.,
RA Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., Antal Z.,
RA Atanasova L., Cervantes-Badillo M.G., Challacombe J., Chertkov O.,
RA McCluskey K., Coulpier F., Deshpande N., von Doehren H., Ebbole D.J.,
RA Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F.,
RA Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R.,
RA Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E.,
RA Lucas S., Luebeck M., Luebeck P.S., Margeot A., Metz B., Misra M.,
RA Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E.,
RA Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S.,
RA Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M.,
RA Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.;
RT "Comparative genome sequence analysis underscores mycoparasitism as the
RT ancestral life style of Trichoderma.";
RL Genome Biol. 12:R40.1-R40.15(2011).
CC -!- SUBUNIT: Component of the ER membrane protein complex (EMC).
CC {ECO:0000256|ARBA:ARBA00011276}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004115}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the EMC1 family.
CC {ECO:0000256|ARBA:ARBA00007904}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK47718.1}.
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DR EMBL; ABDG02000020; EHK47718.1; -; Genomic_DNA.
DR RefSeq; XP_013945911.1; XM_014090436.1.
DR AlphaFoldDB; G9NNS7; -.
DR STRING; 452589.G9NNS7; -.
DR GeneID; 25776248; -.
DR eggNOG; KOG2103; Eukaryota.
DR HOGENOM; CLU_005034_0_1_1; -.
DR OMA; SWAEVYH; -.
DR OrthoDB; 37872at2759; -.
DR Proteomes; UP000005426; Unassembled WGS sequence.
DR GO; GO:0072546; C:EMC complex; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR026895; EMC1.
DR InterPro; IPR011678; EMC1_C.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR21573:SF0; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR21573; UNCHARACTERIZED; 1.
DR Pfam; PF07774; EMC1_C; 1.
DR Pfam; PF13360; PQQ_2; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 2.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005426};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..971
FT /note="ER membrane protein complex subunit 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003525103"
FT TRANSMEM 938..958
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 737..967
FT /note="ER membrane protein complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07774"
SQ SEQUENCE 971 AA; 105394 MW; 8CEAF25CF21EBDEA CRC64;
MRRTLQSVLL LGLSSLAAAI FQDEVDDIDF HHALVGVPQV ETTFFHRPKK DEKASYLYTL
SDVGILGAVN PNSGALVWRQ QIADGVSNGG GHLRAPEGEN WVAAAYGQRV QSWAALSGRN
LWEVEFGGEV KDLEIMELTE SARKDVLVLS EEDGVTVLRR LHGALGTTVW EFREVSKDIP
LQVSTSLTNV YVVSLHGSPS SYSLKVTSLE PATGGRVDHW TVGTKGEVHE SKDVMFVGAN
SAAPILAWAS NDLTKLNVHV LGTKTKQEFP LIADTVSVTI HAPHLIQSQP HFLVHTRTTT
GNKGEVFHTD LKTGRITKAY ELPLLPGLGT FSTSSEGANV YFTRVTEDEV LVVSSDSHSI
LARNSLDPEA RTGAIHAVSE VIKKAGGKEF AIRSATVTAA QDWILIRNGK LDWTRHEGLS
GAVAAAWAEI PEAEDLAKVL AEEAHTNPWN AYVHRLTRHI NDLQYLPDYL ASVPTRVIES
ITGGAVLVSK TEGLHRDSFG FNKIIILATR RGQFYALDTG NHGQVVWSAD VFPQFPGAAL
EVKGIVVNDS EGTVTVRGSK GEFAVITVAD GKILEVHYGD DSAVVSSTAV VGSDGSKWLL
AFDQDRKPIV DALKGRSLDQ TIVIRDENDI IKGVKFSDED GQVTRNEIWQ LQLLPGQKIV
SIAKLPPHDP IASIGRVLGD RTVNYKYLNP NIIVVAAIDN AAAALSVYVV DTVSGQLLAS
QVYDGVDGDK DISCTLSENW YSCAFFGQYT LDDGTNRDIK GYQVVVSDLY ESPNPNDRGP
LGEAETFSPL DPVDTPTGVP LPWVVSQTWI ISEPLTNLTV TETRQGISNR QLLAYLPESH
AVLGITRHGI DPRRPVGRDP SAAEMEAEGL MKYTPAIQID GRNLLTHERD IVGVRGIVAT
PAVVESTSLV VAYGIDVFGS QVAPSGTFDI LGKGFNKITL LGTVVALTWG VVILAPMVRR
KQINRKWEAF L
//
