ID G9P0P7_HYPAI Unreviewed; 1473 AA.
AC G9P0P7;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Multidrug resistance-like protein {ECO:0000313|EMBL:EHK43198.1};
GN ORFNames=TRIATDRAFT_294283 {ECO:0000313|EMBL:EHK43198.1};
OS Hypocrea atroviridis (strain ATCC 20476 / IMI 206040) (Trichoderma
OS atroviride).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=452589 {ECO:0000313|EMBL:EHK43198.1, ECO:0000313|Proteomes:UP000005426};
RN [1] {ECO:0000313|EMBL:EHK43198.1, ECO:0000313|Proteomes:UP000005426}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20476 / IMI 206040 {ECO:0000313|Proteomes:UP000005426};
RX PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40;
RA Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A.,
RA Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A.,
RA Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., Antal Z.,
RA Atanasova L., Cervantes-Badillo M.G., Challacombe J., Chertkov O.,
RA McCluskey K., Coulpier F., Deshpande N., von Doehren H., Ebbole D.J.,
RA Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F.,
RA Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R.,
RA Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E.,
RA Lucas S., Luebeck M., Luebeck P.S., Margeot A., Metz B., Misra M.,
RA Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E.,
RA Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S.,
RA Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M.,
RA Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.;
RT "Comparative genome sequence analysis underscores mycoparasitism as the
RT ancestral life style of Trichoderma.";
RL Genome Biol. 12:R40.1-R40.15(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK43198.1}.
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DR EMBL; ABDG02000026; EHK43198.1; -; Genomic_DNA.
DR RefSeq; XP_013941416.1; XM_014085941.1.
DR SMR; G9P0P7; -.
DR STRING; 452589.G9P0P7; -.
DR GeneID; 25780379; -.
DR eggNOG; KOG0054; Eukaryota.
DR HOGENOM; CLU_000604_27_5_1; -.
DR OMA; NMLIQFW; -.
DR OrthoDB; 2301395at2759; -.
DR Proteomes; UP000005426; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18579; ABC_6TM_ABCC_D1; 1.
DR CDD; cd18580; ABC_6TM_ABCC_D2; 1.
DR CDD; cd03250; ABCC_MRP_domain1; 1.
DR CDD; cd03244; ABCC_MRP_domain2; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR044746; ABCC_6TM_D1.
DR InterPro; IPR044726; ABCC_6TM_D2.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24223:SF399; ABC TRANSPORTER ATNG; 1.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000005426};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1473
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003524973"
FT TRANSMEM 68..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 907..933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 953..977
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1022..1042
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1048..1064
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1133..1154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 315..589
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 627..855
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 918..1191
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1228..1462
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1473 AA; 160674 MW; 9E2BA95E522BC26C CRC64;
MSSIPPLFFF IFTSILLNPS EKKKICSCPV MNTSSTPLCA PTADAAFGPV VDAACRDGFD
LTLVFEQSVF VLLPAAMLVL MAPLRLVQLR KSPVKVAGYA SRMIKLSVTG CLATLQLVLI
ALWATHHGPA RLNSVSVAAA SISFISSLVA CALSYYEHAR SLHPSSLLNL FLLASLLLDA
AVLRTVWIAL SATAIQAVLT ASFALKTALL VLEAREKASH VVGRPTLAPE ETSGLYSRAV
FAWVAPLLRT GFRRLLRPAD LFPLDEAMSV SSLSERFWWH WRKASPSTQA SKHRLVLCCI
ATLRSALFAV LVPRLALLAF TICQPLVLTR FLGFLNDESQ SVKIGYGLVG AYGLVYTGIA
ATQALYWHQN GRCVTMLRGI LVSAVFSKVT QVSVVAIDDS AALTLMSSDV DVIVRAMREI
HEFWANIIQI AIATWLLSQQ IGYAAAGPII VSAISLVATM LVSPLAKKYR VGWLEMTQKR
VGITSAMIGH IKSIKMSGLS KHLSDTIAAL RVQEIAASKP FRVVGAVTSS VAQVPLLLSP
VLAFAMFQGV TAATGQVLDP TRMFAALSLI TLSAQPLFWI FEVILNLSAA FGAFDRIQSF
LVKSTRDEYR MMEVANIANS AAGVAVIDVE DATFDWSQDR SVLSNVTFSL SSGQFTLLIG
PIASGKTTLL KGLLGEVPHS KGKVYMARGS LSWCEQTPWI MNQTIRDNII GYSHFDQDLY
DQTVQACELE QDFGQLPQGD FTVVGSKGLA LSGGQKQRVA LARAVYSRPQ IALFDDIFSG
LDNATSQRIF NNLFSSNTGL LRKWKTTILL ATQSVDFLPS ADHVIALGRQ GKITEQGSFE
RLLISHGYVQ NLMGNTSIVS VTDAHQDEII SESAAEASVP KVEYKAKQVE VKDDKRRQTG
DSTVYKYYFG SIGTVFIIAL LVFEVVWAFL QSFPTVWLEF WSDSNAQGHN RSGLYLGVYA
VLQIVGVFWF VLVAIAAKSG ISLHHRLLSA VISAPLSLFT TTDLGAITTR FSQDIGILDN
NLPLALVITI ASFFGVLARA GLLAASSYYV AISFPFLAAL YYFLQRGYLR TSRQLRLLDL
EEKAPVYTQF METLSGISTI RAFGWQKQAI LKNHQLVDRS QQPFYLLIMV QRWLVLVLDL
ITTALALLVV GFAVKLRGSV SVGLAGVSLV QLISMSETLN MLIQFWTSIE TSIGAVARIK
QFAEETPNES LLGEDQEPPA DWPSRGHVVI RDLEASYGEN GDIKALEGVT LDLKPGEKVG
VCGRTGSGKS SLLLTILRLL DPSSGTLTID SIPLNTISRE VIRSRLITVA QDQFVLPGTI
RQNIDPSSSY PESAVIGALQ AVNLWAAIDA RGGLDAVFAE DMLSHGQKQL FFLARAVLKK
DCGKVVLLDE ASSSLDKETE QMVRTTINTR FKNHTVISIA HHLATILDFD RVVVMDKGRV
VEVGSPRELL QSPGRGKFKA LWEANSRGTM DEE
//
