ID G9WNN4_9FIRM Unreviewed; 718 AA.
AC G9WNN4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=EAL domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF9625_00967 {ECO:0000313|EMBL:EHL10771.1};
OS Oribacterium parvum ACB1.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Oribacterium.
OX NCBI_TaxID=796943 {ECO:0000313|EMBL:EHL10771.1, ECO:0000313|Proteomes:UP000018461};
RN [1] {ECO:0000313|Proteomes:UP000018461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACB1 {ECO:0000313|Proteomes:UP000018461};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cuomo C., Becnel J., Sanscrainte N., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACB1 {ECO:0000313|Proteomes:UP000018461};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Ward D., Feldgarden M., Gevers D., Sizova M., Hazen A.,
RA Epstein S., Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M.,
RA Haas B., Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M.,
RA Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A., Larimer J.,
RA McCowan C., Murphy C., Pearson M., Poon T.W., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Oribacterium sp. ACB1.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHL10771.1}.
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DR EMBL; AFZC01000017; EHL10771.1; -; Genomic_DNA.
DR RefSeq; WP_009534823.1; NZ_KE148312.1.
DR AlphaFoldDB; G9WNN4; -.
DR STRING; 796943.HMPREF9625_00967; -.
DR GeneID; 84785098; -.
DR PATRIC; fig|796943.3.peg.1385; -.
DR HOGENOM; CLU_000445_70_57_9; -.
DR Proteomes; UP000018461; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF78; CYCLIC DI-GMP PHOSPHODIESTERASE PDEI-RELATED; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000018461}.
FT DOMAIN 46..169
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 178..430
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 718 AA; 82409 MW; 26CB2DFB60D5E89E CRC64;
MNSNQNPLLP KWIEKRNQLR EGDFDSLSKT IKNQLFRELA TEFMEEGQLL CYFNIVDFKL
YNDRFGFEMG DALLVEMANI LQKAFPDALI TRMFADQFAL LSKEKDCVDT LISAHEDFLN
LKIPMALDFK VGIYSISAKK NIINACDRAK TACDCIKKER AVFYRFYDEE LSHLLLQHRF
IVDHIEKAIE NGDIYVYYQP LIRALSKEVC GLEALVRWID PQFGMFSPAE FIPVLEEYHL
IHLLDIHVIS LICQEFAAIR ERGEEMIPVS LNLSRMDFEL CDIFGELEKL VEKYQVPREL
LTLEITESVL SKSPALISSR IKRFHEAGYK VWMDDFGSGY SSLNVLKDFD FDLIKIDMML
LQDSNEKSRK IISSIVDMAK KIGIRTLAEG VETEEQLDFL REIGCEKLQG YYIGRPGPYQ
NSILHCKENG FRFESPGKRQ YNDDLGYINL LSNGCLPPSA LEEKEDIAPG IPLSIVEMLG
DRIEFLYVNQ SFQRELAIAD GLSVQETERL INDKNTAQYK QIRSFLSALS EGGGSDMDTI
EGDSLCSIRG KEISHIPGRN AYLLNIQVYR GDFLKLKQKK MMDKVKDLYN GYELVLLWNP
SLGQNELLYE KSHGSLAPGD RDFLTEYAKT TFSKSEEKRF FQFLRKNNVI RDKETVKEEA
FFGRDREGKK RIFLVSLKPS ALENGTKVLL SVRRVWNPGI AKLVAGGLGN KDPIRKDA
//
