ID GBB3_TOBAC Reviewed; 375 AA.
AC Q40507;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 08-NOV-2023, entry version 96.
DE RecName: Full=Guanine nucleotide-binding protein subunit beta;
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Samsun NN; TISSUE=Leaf;
RA Kusnetsov V.V., Oelmueller R.;
RT "Isolation and characterization of cDNAs encoding the subunit beta of
RT heterotrimeric G proteins from N. tabacum.";
RL (er) Plant Gene Register PGR96-048(1996).
CC -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC as a modulator or transducer in various transmembrane signaling
CC systems. The beta and gamma chains are required for the GTPase
CC activity, for replacement of GDP by GTP, and for G protein-effector
CC interaction.
CC -!- SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.
CC -!- SIMILARITY: Belongs to the WD repeat G protein beta family.
CC {ECO:0000305}.
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DR EMBL; X98161; CAA66842.1; -; mRNA.
DR PIR; T03256; T03256.
DR AlphaFoldDB; Q40507; -.
DR SMR; Q40507; -.
DR STRING; 4097.Q40507; -.
DR PaxDb; 4097-Q40507; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IBA:GO_Central.
DR GO; GO:0030159; F:signaling receptor complex adaptor activity; IBA:GO_Central.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR001632; Gprotein_B.
DR InterPro; IPR016346; Guanine_nucleotide-bd_bsu.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19850; GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA; 1.
DR PANTHER; PTHR19850:SF25; GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-1; 1.
DR Pfam; PF00400; WD40; 7.
DR PIRSF; PIRSF002394; GN-bd_beta; 1.
DR PRINTS; PR00319; GPROTEINB.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat; Transducer; WD repeat.
FT CHAIN 1..375
FT /note="Guanine nucleotide-binding protein subunit beta"
FT /id="PRO_0000127729"
FT REPEAT 63..93
FT /note="WD 1"
FT REPEAT 105..135
FT /note="WD 2"
FT REPEAT 154..185
FT /note="WD 3"
FT REPEAT 202..233
FT /note="WD 4"
FT REPEAT 246..276
FT /note="WD 5"
FT REPEAT 293..323
FT /note="WD 6"
FT REPEAT 339..369
FT /note="WD 7"
SQ SEQUENCE 375 AA; 40812 MW; 72D53D1DFC5CF598 CRC64;
MSVTELKERH MAATQTVSDL REKLKQKRLQ LLDTDVSGYA RSQGKTPVTF GPTDLVCCRI
LQGHTGKVYS LDWTPEKNRI VSASQDGRLI VWNALTSQKT HAIKLPCAWV MTCAFSPSGQ
SVACGGLDSV CSIYNLNSPI DKDGNHPVSR MLSGHKGYVS SCQYVPDEDT HLITSSGDQT
CVLWDITTGL RTSVFGGEFQ SGHTADVQSV SISSSNPRLF VSGSCDTTAR LWDNRVASRA
QRTFYGHEGD VNTVKFFPDG NRFGTGSEDG TCRLFDIRTG HQLQVYYQPH GDGDIPHVTS
MAFSISGRLL FVGYSNGDCY VWDTLLAKVV LNLGGVQNSH EGRISCLGLS ADGSALCTGS
WDTNLKIWAF GGTEV
//
