ID GDAP2_NEMVE Reviewed; 502 AA.
AC A7T167;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-OCT-2007, sequence version 1.
DT 24-JAN-2024, entry version 65.
DE RecName: Full=Protein GDAP2 homolog;
GN Name=gdap2; ORFNames=v1g195342;
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6;
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SIMILARITY: Belongs to the GDAP2 family. {ECO:0000305}.
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DR EMBL; DS470082; EDO30294.1; -; Genomic_DNA.
DR RefSeq; XP_001622394.1; XM_001622344.1.
DR AlphaFoldDB; A7T167; -.
DR SMR; A7T167; -.
DR EnsemblMetazoa; EDO30294; EDO30294; NEMVEDRAFT_v1g195342.
DR GeneID; 5501034; -.
DR KEGG; nve:5501034; -.
DR eggNOG; KOG2633; Eukaryota.
DR HOGENOM; CLU_026877_0_0_1; -.
DR InParanoid; A7T167; -.
DR OMA; VHLFRYV; -.
DR OrthoDB; 1105329at2759; -.
DR PhylomeDB; A7T167; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR CDD; cd02905; Macro_GDAP2-like; 1.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR002589; Macro_dom.
DR InterPro; IPR043472; Macro_dom-like.
DR InterPro; IPR035793; Macro_GDAP2.
DR PANTHER; PTHR11106; GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED; 1.
DR PANTHER; PTHR11106:SF72; GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF01661; Macro; 1.
DR SMART; SM00506; A1pp; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF52949; Macro domain-like; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS51154; MACRO; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..502
FT /note="Protein GDAP2 homolog"
FT /id="PRO_0000331404"
FT DOMAIN 40..221
FT /note="Macro"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00490"
FT DOMAIN 329..486
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00056"
SQ SEQUENCE 502 AA; 56944 MW; E2D9EBA2F2C8C2FD CRC64;
MDPLGATANL VDINSLPKWS TTPVPNYEPG SNESQSSSFL SPFPVDEEIN AKVVLWNGDI
TKLAADAIVN TTNESLSDRG ALSERVHRAA GPELMQECRQ QLLGCRTGEA KISEGYNLPA
RYVIHTVGPR YNTKYKTAAE SALFSCYRNT MRLVRENKIS TIGVCVVNTT KRGYPPEDGA
HIALRTVRRF LEKYGSAVDT VAFVVEGAEA VVYAKVMPIY FPRDKLEEAH ALTLMPDDIG
NEEGEPIIPE RQIRIVPKPP SLQHGEDVEE AEEAEGHLDM TELHVGKHAF AVMAGDHDQM
TKQRAHRSDD GMKVVEQQRV YQRWLRRART ENFADFSRQK ILYQSGVDFL GRPVVVFVAR
HFTAQNTDLG KAVAYFISVL DRIVNRDYVV VYFHTHSTEE NQPPMSFLKE LYHIVDNKYR
RNLKAFYIVH PTVWARIVTW FFTTFTASSV KEKVHFLSGV QYLYDWINPD QLDIPAYVLE
YDMKENGTNY HTPASTYRTG GL
//
