ID   GLGS_SHIFL              Reviewed;          66 AA.
AC   Q7UBJ0; Q83Q49;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   27-MAR-2024, entry version 104.
DE   RecName: Full=Surface composition regulator {ECO:0000255|HAMAP-Rule:MF_00525};
GN   Name=glgS {ECO:0000255|HAMAP-Rule:MF_00525};
GN   OrderedLocusNames=SF3089, S3294;
OS   Shigella flexneri.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Major determinant of cell surface composition. Negatively
CC       regulates motility, adhesion and synthesis of biofilm
CC       exopolysaccharides. {ECO:0000255|HAMAP-Rule:MF_00525}.
CC   -!- SIMILARITY: Belongs to the GlgS family. {ECO:0000255|HAMAP-
CC       Rule:MF_00525}.
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DR   EMBL; AE005674; AAN44566.2; -; Genomic_DNA.
DR   EMBL; AE014073; AAP18379.1; -; Genomic_DNA.
DR   RefSeq; NP_708859.2; NC_004337.2.
DR   RefSeq; WP_005051912.1; NZ_WPGV01000243.1.
DR   AlphaFoldDB; Q7UBJ0; -.
DR   SMR; Q7UBJ0; -.
DR   STRING; 198214.SF3089; -.
DR   PaxDb; 198214-SF3089; -.
DR   GeneID; 1026658; -.
DR   KEGG; sfl:SF3089; -.
DR   KEGG; sfx:S3294; -.
DR   PATRIC; fig|198214.7.peg.3666; -.
DR   HOGENOM; CLU_185971_0_0_6; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:1902201; P:negative regulation of bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-UniRule.
DR   GO; GO:1900191; P:negative regulation of single-species biofilm formation; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.970.20; Glycogen synthesis protein GlgS; 1.
DR   HAMAP; MF_00525; GlgS; 1.
DR   InterPro; IPR015065; GlgS.
DR   InterPro; IPR036295; GlgS_sf.
DR   Pfam; PF08971; GlgS; 1.
DR   SUPFAM; SSF109747; Glycogen synthesis protein GlgS; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..66
FT                   /note="Surface composition regulator"
FT                   /id="PRO_0000071604"
SQ   SEQUENCE   66 AA;  7906 MW;  D1F61B6FCB667523 CRC64;
     MEHSLNSLNN FDFLARSFAR MHAEGRPVDI LAVTGNMDEE HRTWFCARYA WYCQQMMQAR
     ELELEH
//