ID H0A3H4_9PROT Unreviewed; 1340 AA.
AC H0A3H4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Beta-ketoacyl synthase protein {ECO:0000313|EMBL:EHL99001.1};
DE Flags: Fragment;
GN ORFNames=HMPREF9946_03367 {ECO:0000313|EMBL:EHL99001.1};
OS Acetobacteraceae bacterium AT-5844.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae.
OX NCBI_TaxID=1054213 {ECO:0000313|EMBL:EHL99001.1, ECO:0000313|Proteomes:UP000003292};
RN [1] {ECO:0000313|EMBL:EHL99001.1, ECO:0000313|Proteomes:UP000003292}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AT-5844 {ECO:0000313|Proteomes:UP000003292};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHL99001.1}.
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DR EMBL; AGEZ01000101; EHL99001.1; -; Genomic_DNA.
DR STRING; 1054213.HMPREF9946_03367; -.
DR eggNOG; COG3321; Bacteria.
DR HOGENOM; CLU_000022_35_7_5; -.
DR Proteomes; UP000003292; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020807; PKS_DH.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF21089; PKS_DH_N; 1.
DR Pfam; PF14765; PS-DH; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00826; PKS_DH; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000003292}.
FT DOMAIN 2..423
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT NON_TER 1340
FT /evidence="ECO:0000313|EMBL:EHL99001.1"
SQ SEQUENCE 1340 AA; 139817 MW; C8A19D770C771585 CRC64;
MGMPIAIIGA ACRLPGAEDL GSFWHLIASG TDAVSHIPAD RFALSAYQHP RKSEPGRAYT
FAAAHLGDIS QFDAPAFGLS PREAAEMDPQ QRVLLEVAAQ AVEDAGWPAS RLAGRAIGAF
VGGSSTDYAE LRLGDPAGID RYFMTGNTLS ILSNRLTNIF DLRGAGQTVD TACSSSLVAL
HMAVQALRSG QIEAALVGGV QLLLSPYAFT GFSRAGMLSQ RGRCQAFDAA ADGYVRGEGA
GVVLLKPLAQ AIADGDRVRG VILGTGTNAA GRTIGLSLPN REAQAALLTQ VLAETGIDRE
DFAYFEAHGT GTQAGDPVET WAIGRALARG RTAPLPIGSV KTNIGHLEPA SGIAGLLKAM
LVLEKGVLPP NLHFNNPNPN IDFQGLNLRV PTAPEAIETT PRSVAGVNSF GFGGTNATVM
LGAAPAPAAL PEASAAPLPP LLLTAHSEAA LKTLATNWQA TLAGPEEAGP RFPALLRGAA
RFRDLHPHRL ALRAETPGAL SALIEEWLAG ENPAAATQGT ARAKVEGPVA FVFSGNGAQH
AGMAREAMAH NAVFRAAIEE ADAVLAPLTG WSGARKLAEG VTAEELAGTD YAQPLLFLVQ
YGIVAVLAAE GIRPGLVLGH SVGEVAAACA AGILTLSQAA RLVVARSRAQ HTRRGHGRMA
AIGASEANAA PLMAACGEED GWALEIAAYN APDAITVAGP PGPIAAVVAE AKKRRLPAVQ
LDLDYAFHST AMDPVRDALA ADLKGLAPAQ GHLPFFSTVT GALKPGLDLD AEYWWHNLRA
PVRFQAAVQA AVDAGARLFI EIGPNPIMQS YLRDNLRAAE AEAPVLATLS RRDGEGDPFP
AIADRAFVHG ADPRPGAAYA GPAMRDGLPA TPFARQRHWF ASTVEAARLT DPVQDHPLLG
FRQGTEPTRW SRILDSTLEP WLADHALMGE AVLPAAGMAD MALAAAALHF PEAPALELRE
LQLLRTLPVA KDSAREVRLS LEAESGLFRI ESRPRLSAEA WTLHARGQVG PATLAALPEA
SIADPACDAA NAHSVSGESL MATAQGFGLH YGPAFRPVRE VRIAPDGASA IARLALPPEA
PADDAGWLLH PVRLDGALQG LLELMAQDGV EEGKAVVPVR FGRLVVRRGT TLPVRAELRV
LHRGERSGQC AVLLRDGAGR VVARLDDAWM QGIRLSPRQQ LADAVFRVEE QPTLPAIPTP
AGIDLTAAIE AALAEDEAAD QTETALLLEG HVLAAAHAAL LAKAGKDGTL SAQGLSPYAR
AQVEMLAEDG LAEATATGWR LLPGEDLPAA TDIWQAVLTE SPTLAHELAW LALAAERLPA
ALDGQSQPEA LPPADAAGFA
//
