ID H0AET4_HALSG Unreviewed; 660 AA.
AC H0AET4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=DNA replication initiator (Cdc21/Cdc54) {ECO:0000313|EMBL:EHK00700.1};
GN ORFNames=HRED_00648 {ECO:0000313|EMBL:EHK00700.1};
OS Haloredivivus sp. (strain G17).
OC Archaea; Euryarchaeota; Stenosarchaea group; Candidatus Nanohaloarchaea;
OC Candidatus Haloredivivus.
OX NCBI_TaxID=1072681 {ECO:0000313|EMBL:EHK00700.1, ECO:0000313|Proteomes:UP000003484};
RN [1] {ECO:0000313|EMBL:EHK00700.1, ECO:0000313|Proteomes:UP000003484}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G17 {ECO:0000313|EMBL:EHK00700.1,
RC ECO:0000313|Proteomes:UP000003484};
RA Ghai R., Pasic L., Fernandez A.B., Martin-Cuadrado A.-B., Mizuno C.M.,
RA McMahon K.D., Papke R.T., Stepanauskas R., Rodriguez-Brito B., Rohwer F.,
RA Sanchez-Porro C., Ventosa A., Rodriguez-Valera F.;
RT "New Dominant Microbial Groups Along A Salinity Gradient.";
RL Sci. Rep. 0:0-0(2011).
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|ARBA:ARBA00008010,
CC ECO:0000256|RuleBase:RU004070}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHK00700.1}.
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DR EMBL; AGNT01000394; EHK00700.1; -; Genomic_DNA.
DR AlphaFoldDB; H0AET4; -.
DR Proteomes; UP000003484; Unassembled WGS sequence.
DR GO; GO:0042555; C:MCM complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 3.30.1640.10; mini-chromosome maintenance (MCM) complex, chain A, domain 1; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR008047; MCM_4.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR048907; MCM_WH.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF43; DNA REPLICATION LICENSING FACTOR MCM6; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR Pfam; PF21120; MCM_WH_arc; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR PRINTS; PR01660; MCMPROTEIN4.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070};
KW Reference proteome {ECO:0000313|Proteomes:UP000003484}.
FT DOMAIN 265..471
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
SQ SEQUENCE 660 AA; 73991 MW; 3D30F1D7CC4C74FD CRC64;
MDYGEAVTEF EEFFTEKYEQ EVLSAEKQGK DSVIVEFKDL DMFKPEITDY LKEEPEKALD
AASEGVMAVD ILKEELNVRI RNMPEEDYVL LKNLRSEHIG KFVPVEGMIK RASQVKPEVV
SAVFECTQCG DRYTKEQDSS QLKSPYKCEC GSKRFDPVEK NMTDTQIVTL EENPESREGS
EQPSSLSVRL EGDLVDPEFQ RKVVPGNVVE VTGIVRERPI KKNSKKFDIY MEANNVEPRQ
QEFEQLELEE DEIEEIREMA SDENIFGRIT ESIAPSIFGH DRIKEAIALQ LFGGVRKTRE
DGVKSRGDLH ILLIGEPGTG KSQLLKFAGE LAPKGRYVVG KSSTGAGLTA SVVKEESTGE
FSLEAGAVVL AHKGMAAIDE IDKMSVEDRS SLHEAMEQQQ ISVSKANIQA TLNAQTSILA
AGNPKLGRFD PYEPIPEQIN IGDTLLSRFD FIFPVKDEPD QDRDNKLANQ ILANHREPED
QDAEISQEKL RKYVAYAKKN VRPDLTEEAS DLIQDFYVSM RSSGDEDSVP ITARQLEAMV
RIAEASARAQ LKDQVEESDA QRAIDILKYT LEQVGMDPET GDFDIDRIES GVSSSQRNRI
QTIKHLIDEL AGDDGSAEIE AVIEAAESED ISSEKTEEVI EKLKREGELF EPKQGFVQKI
//
