ID H0C254_9BURK Unreviewed; 394 AA.
AC H0C254;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Muconate and chloromuconate cycloisomerase {ECO:0000313|EMBL:EHL21379.1};
GN ORFNames=KYG_18781 {ECO:0000313|EMBL:EHL21379.1};
OS Acidovorax sp. NO-1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Acidovorax.
OX NCBI_TaxID=512030 {ECO:0000313|EMBL:EHL21379.1, ECO:0000313|Proteomes:UP000003485};
RN [1] {ECO:0000313|EMBL:EHL21379.1, ECO:0000313|Proteomes:UP000003485}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NO-1 {ECO:0000313|EMBL:EHL21379.1,
RC ECO:0000313|Proteomes:UP000003485};
RX PubMed=22374962; DOI=10.1128/JB.06814-11;
RA Huang Y., Li H., Rensing C., Zhao K., Johnstone L., Wang G.;
RT "Genome Sequence of the Facultative Anaerobic Arsenite-Oxidizing and
RT Nitrate-Reducing Bacterium Acidovorax sp. Strain NO1.";
RL J. Bacteriol. 194:1635-1636(2012).
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- PATHWAY: Aromatic compound metabolism. {ECO:0000256|ARBA:ARBA00005211}.
CC -!- SIMILARITY: Belongs to the mandelate racemase/muconate lactonizing
CC enzyme family. {ECO:0000256|ARBA:ARBA00008031}.
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DR EMBL; AGTS01000105; EHL21379.1; -; Genomic_DNA.
DR RefSeq; WP_008906399.1; NZ_AGTS01000105.1.
DR AlphaFoldDB; H0C254; -.
DR STRING; 512030.KYG_18781; -.
DR PATRIC; fig|512030.4.peg.3713; -.
DR OrthoDB; 5596677at2; -.
DR UniPathway; UPA00083; -.
DR Proteomes; UP000003485; Unassembled WGS sequence.
DR GO; GO:0018850; F:chloromuconate cycloisomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0018849; F:muconate cycloisomerase activity; IEA:InterPro.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR CDD; cd03318; MLE; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR013370; Chloromuconate_cycloisomerase.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR NCBIfam; TIGR02534; mucon_cyclo; 1.
DR PANTHER; PTHR48073:SF2; O-SUCCINYLBENZOATE SYNTHASE; 1.
DR PANTHER; PTHR48073; O-SUCCINYLBENZOATE SYNTHASE-RELATED; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDG01258; (chloro)muconate_cycloisomeras; 1.
DR SFLD; SFLDG00180; muconate_cycloisomerase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR PROSITE; PS00909; MR_MLE_2; 1.
PE 3: Inferred from homology;
KW Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:EHL21379.1};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Reference proteome {ECO:0000313|Proteomes:UP000003485}.
FT DOMAIN 148..246
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 394 AA; 42448 MW; 0B39FFDDE419D9F3 CRC64;
MQSRFTVERM QARILDIPTI RPHKLSFGSI SRQSPVIVQV WLKNGATGFG EAATIGGPSW
NEESPESILH AIQNYLAPAL VGQDAGGFEA ALARMDKACK GNAFAKSAVE MALIDAVART
LGLPAWQLLG GKVHQSLPLA WTLASGDVDR DLQEAHLRLT QKRHHIFKMK IGARAPQDDV
AHVTQIARGL QGQATLTVDV NQAWDGNTAR RYLPQLVEAG VTLIEQPVAQ WNVEALKHLT
ATLDGALIMA DETVCTPQDA MMLAREKASH VFSLKVAKHG GLIRTRKVAA IAEAADIGWY
GGTMLETSLG SAASAHVFAT LGSQHHGCEL FGPQLLVDDI VESQMPIVDF ELQLPDGPGF
GVEVSLAQLE RFDRARQGLT AVHVDMAAHT PTPV
//
