ID H0E2W6_9ACTN Unreviewed; 731 AA.
AC H0E2W6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Formate dehydrogenase-O major subunit {ECO:0000313|EMBL:EHN11983.1};
DE EC=1.2.1.2 {ECO:0000313|EMBL:EHN11983.1};
GN ORFNames=PAI11_11310 {ECO:0000313|EMBL:EHN11983.1};
OS Patulibacter medicamentivorans.
OC Bacteria; Actinomycetota; Thermoleophilia; Solirubrobacterales;
OC Patulibacteraceae; Patulibacter.
OX NCBI_TaxID=1097667 {ECO:0000313|EMBL:EHN11983.1, ECO:0000313|Proteomes:UP000005143};
RN [1] {ECO:0000313|EMBL:EHN11983.1, ECO:0000313|Proteomes:UP000005143}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=I11 {ECO:0000313|EMBL:EHN11983.1,
RC ECO:0000313|Proteomes:UP000005143};
RX PubMed=23212173; DOI=10.1007/s10532-012-9610-5;
RA Almeida B., Kjeldal H., Lolas I., Knudsen A.D., Carvalho G., Nielsen K.L.,
RA Barreto Crespo M.T., Stensballe A., Nielsen J.L.;
RT "Quantitative proteomic analysis of ibuprofen-degrading Patulibacter sp.
RT strain I11.";
RL Biodegradation 24:615-630(2013).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHN11983.1}.
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DR EMBL; AGUD01000052; EHN11983.1; -; Genomic_DNA.
DR RefSeq; WP_007571895.1; NZ_AGUD01000052.1.
DR AlphaFoldDB; H0E2W6; -.
DR PATRIC; fig|1097667.3.peg.1129; -.
DR OrthoDB; 7376058at2; -.
DR Proteomes; UP000005143; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR PANTHER; PTHR43105:SF14; POSSIBLE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:EHN11983.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005143}.
FT DOMAIN 1..55
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 731 AA; 76898 MW; 98053332253ED5AB CRC64;
MPVRTCPFCE ATCGLEVTLD GDRVVKVRGD ADDVFSKGFV CPKGTSLKQL HEDPDRVRRP
LVKQPDGSFA EVGWDAAFER IAELWAPFVG SDDRDAVGVY LGNPSAHSFG PLLYGRVLLK
ALRTRSIFSA STLDQYPKQL AAAHLFGSGA TVPVPDLDRT DHLLILGANP VVSNGSLMTA
PDVRGRIHAI QARGGKVVVV DPRRTRTVQE ADQHIAIRPG GDALWLMALL QVLASEGLMT
PGEHLAGLDE VVAAAEPFTP EAVAAATGVD PEVTRTAARE LAAAPTACVY GRIGTTTQRF
GSTASWLVDV LNAVTGNLDR PGGAMFPLPA HAKRGAGRGR GARFGRWSSR IRGAGEVFGE
LPAACLAEEL ETPGAGQIRA LITVAGNPVL SAPGGERLAR ALPGLEAYVA IDIYVNETTR
HADVILPAPS PLEKAHYDLA LYGFAIRNVA NYSPPLLERD GLDEWQSLLR LLGVVTGQGP
DADVAAIDGF VARALVEKEV GDERSALHGQ DVDAVMAQLQ PRVGPDRLLD LLLRGGAYGL
TLADLEAAPH GIDLGPLQPR LPEILSTPSG RVELAPPDLL ADVERLALAL DEDAGGMVLI
GRRDLRSNNS WMHNLPVLVS GPERCTAWLH PDDATRLGVA DGDPVRISSR VGAIEVPATV
TDRIRPGVVS VPHGWGHGGD GVALAVARGV AGVNSNALSD DDQLEPLSGT AVLNGIPVEV
VAVAAGEPVP A
//
